GTF2H1
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Official Full Name
general transcription factor IIH, polypeptide 1, 62kDa -
Overview
General transcription factor IIH subunit 1 is a protein that in humans is encoded by the GTF2H1 gene. -
Synonyms
GTF2H1;general transcription factor IIH, polypeptide 1, 62kDa;general transcription factor IIH, polypeptide 1 (62kD subunit);general transcription factor IIH subunit 1;BTF2;BTF2 p62;basic transcription factor 2 62 kDa subunit;general transcription
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- Non
- His
- T7
- GST
- Myc&DDK
Involved Pathway
GTF2H1 involved in several pathways and played different roles in them. We selected most pathways GTF2H1 participated on our site, such as Basal transcription factors,Nucleotide excision repair,Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2H1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Basal transcription factors | TBPL2,ERCC2,CCNH,TAF8,TAF7,TAF13,ERCC3,GTF2F1,GTF2H2C_2,GTF2H5 |
| Nucleotide Excision Repair | XPC,COPS6,GTF2H2,ZNF830,GPS1,ERCC5,CCNH,INO80B,POLD1,GTF2H5 |
| Viral carcinogenesis | HIST1H4E,TRP53,GRB2,HDAC10,CASP8,GTF2A1L,HDAC9,NFKB1,HIST1H4K,PIK3CD |
Protein Function
GTF2H1 has several biochemical functions, for example, contributes_to DNA-dependent ATPase activity,contributes_to RNA polymerase II carboxy-terminal domain kinase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2H1 itself. We selected most functions GTF2H1 had, and list some proteins which have the same functions with GTF2H1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | TINAGL1,PDK3,SPTLC1,ELK1,BTG1,DKK1B,RPS6KA4,XIAP,CLTC,CXCL11 |
| contributes_to DNA-dependent ATPase activity | GTF2H3,MNAT1,BPTF,GTF2H4,ERCC3,ERCC2,GTF2H2,RBBP4 |
| contributes_to RNA polymerase II carboxy-terminal domain kinase activity | GTF2H4,MNAT1,GTF2H2,GTF2H3,ERCC3,ERCC2 |
| contributes_to protein kinase activity | ERCC3,ERCC2,GTF2H3,GTF2H2,GTF2H4 |
Interacting Protein
GTF2H1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2H1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2H1.
GTF2E1;TP53
Resources
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References
- Liu, M; Zhang, X; et al. MicroRNA-mRNA functional pairs for cisplatin resistance in ovarian cancer cells. CHINESE JOURNAL OF CANCER 33:285-294(2014).
- Gao, C; Tignor, NL; et al. HEFT: eQTL analysis of many thousands of expressed genes while simultaneously controlling for hidden factors. BIOINFORMATICS 30:369-376(2014).
