GTF2E1
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Official Full Name
general transcription factor IIE, polypeptide 1, alpha 56kDa -
Overview
General transcription factor IIE subunit 1 (GTF2E1), also known as transcription initiation factor IIE subunit alpha (TFIIE-alpha), is a protein that in humans is encoded by the GTF2E1 gene. -
Synonyms
GTF2E1;general transcription factor IIE, polypeptide 1, alpha 56kDa;general transcription factor IIE, polypeptide 1 (alpha subunit, 56kD);general transcription factor IIE subunit 1;FE;TFIIE A;General transcription factor IIE 56 kDa subunit;MAL7P1.86;TF2E1;Transcription initiation factor IIE alpha subunit;Transcription initiation factor iie alpha subunit putative;TFIIE-alpha;OTTHUMP00000216144;transcription initiation factor IIE subunit alpha;TFIIE-A
Recombinant Proteins
- Human
- Rhesus macaque
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- Insect Cells
- HEK293
- In Vitro Cell Free System
- Non
- GST
- His
- His&Fc&Avi
- Myc&DDK
Involved Pathway
GTF2E1 involved in several pathways and played different roles in them. We selected most pathways GTF2E1 participated on our site, such as Basal transcription factors,Epstein-Barr virus infection,Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2E1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Basal transcription factors | GTF2F2A,TBP,GTF2A1L,CDK7,GTF2E2,GTF2A1,TAF6L,GTF2H2C,ERCC2,GTF2H5 |
| Viral carcinogenesis | VAC14,PRKACG,CREB3L3,HIST1H4B,IL6ST,HRAS,PRKACB,LTBR,HDAC11,BAX |
| Epstein-Barr virus infection | MAPK13,AKT1,MAPK12,MDM2,LYN,CCNA1,TBP,SPI1,POLR3E,PIK3CD |
Protein Function
GTF2E1 has several biochemical functions, for example, RNA polymerase II core binding,TFIIH-class transcription factor binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2E1 itself. We selected most functions GTF2E1 had, and list some proteins which have the same functions with GTF2E1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II core binding | AGO1,WAC,WACA,SMYD3,PCF11,KIAA1967,KIAA1530,C14orf166,RECQL5,SMYD2B |
| metal ion binding | ZFP13,SP7,ZNF383,JAZF1A,ZMYM2,Amy1,MECOM,ZFP90,PRKCH,NGLY1 |
| transcription factor activity, RNA polymerase II transcription factor binding | SMAD4,SRF,GATA4,MYOCD,LHX2,THRAA,TWIST2,ZNF296,HIF1A,YAP1 |
| protein binding | UTF1,CERK,POP1,WHRN,C16orf59,CYP1A1,CDC42EP1,BCL2L12,PFDN5,SGTB |
| sequence-specific DNA binding | GATA2B,NFIL3-5,POU2F2,NR2F6A,NKX2-5,FOXD4,DBPB,HOXC4A,USF1,FOXQ1 |
| transcription factor activity, core RNA polymerase II binding | GTF2F2,GTF2F2A,GTF2F2B |
Interacting Protein
GTF2E1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2E1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2E1.
GTF2H1;GTF2E2;SRPK2
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