GTF2A1L
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Official Full Name
general transcription factor IIA, 1-like -
Overview
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. -
Synonyms
GTF2A1L;general transcription factor IIA, 1-like;TFIIA-alpha and beta-like factor;ALF;TFIIA alpha/beta like factor;Stonin 1;General transcription factor II A 1 like factor;GTF2A1LF;SALF;TFIIA alpha and beta like factor;GTF2A1-like factor;OTTHUMP00000201062;OTTHUMP00000201165;TFIIA-alpha/beta-like factor;TFIIA large subunit isoform ALF;general transcription factor II A, 1-like factor;Limulus Antilipopolysaccharide Factor;LALF
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Mouse
- P.pastoris
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- Non
- His
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ALF-240L | Recombinant Limulus Antilipopolysaccharide Factor | P.pastoris | Non |
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| GTF2A1L-418H | Recombinant Human GTF2A1L Protein, His-tagged | E.coli | Human | His |
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| GTF2A1L-4478Z | Recombinant Zebrafish GTF2A1L | Mammalian Cell | Zebrafish | His |
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| GTF2A1L-4504C | Recombinant Chicken GTF2A1L | Mammalian Cell | Chicken | His |
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| GTF2A1L-458H | Recombinant Human GTF2A1L Protein, GST-tagged | Wheat Germ | Human | GST |
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| GTF2A1L-7351M | Recombinant Mouse GTF2A1L Protein | Mammalian Cell | Mouse | His |
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| GTF2A1L-5705HCL | Recombinant Human GTF2A1L 293 Cell Lysate | HEK293 | Human | Non |
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| GTF2A1L-1425HF | Recombinant Full Length Human GTF2A1L Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 478 amino acids |
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| GTF2A1L-3987M | Recombinant Mouse GTF2A1L Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| GTF2A1L-3987M-B | Recombinant Mouse GTF2A1L Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
GTF2A1L involved in several pathways and played different roles in them. We selected most pathways GTF2A1L participated on our site, such as Basal transcription factors,Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTF2A1L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Viral carcinogenesis | GTF2E1,RAC1,HIST1H4D,PKM2,HIST2H2BB,RBPJ,HIST1H2BO,TRAF2,STAT5B,CCND3 |
| Basal transcription factors | CDK7,ERCC2,TAF4B,TAF15,GTF2H2,GTF2IRD1,GTF2I,GTF2H3,GTF2H5,GTF2E1 |
Protein Function
GTF2A1L has several biochemical functions, for example, DNA binding,protein binding,transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GTF2A1L itself. We selected most functions GTF2A1L had, and list some proteins which have the same functions with GTF2A1L. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription coactivator activity | MCIN,YAF2,TUBB3,JUP,CTNNB1,SUB1,E4F1,HIF3A,MAML1,PARK7 |
| protein binding | HNRNPU,OSBP2,SDC1,DUSP13,HIST1H4A,ACOT7,CSDC2,DDX17,DKC1,GNMT |
| DNA binding | MSXE,ZNF133,MXI1,HER12,PARPBP,MSL3,Trl,ZNF597,ESRRGB,NKX2.2A |
Interacting Protein
GTF2A1L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTF2A1L here. Most of them are supplied by our site. Hope this information will be useful for your research of GTF2A1L.
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