GSTO1

  • Official Full Name

    glutathione S-transferase omega 1

  • Overview

    The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene.

  • Synonyms

    GSTO1;glutathione S-transferase omega 1;glutathione S-transferase omega-1;GSTTLp28;P28;AA407097;AI194287;AU018802;DKFZp686H13163;EC 2.5.1.18;Glutathione S transferase omega 1;Glutathione S-transferase omega 1-1;Glutathione S-transferase omega;Glutathione transferase omega 1;Glutathione-dependent dehydroascorbate reductase;Glutathione-S-transferase like;Glutathione-S-transferase omega 1;GSTO 1-1;GSTO1 1;GSTX;Gtsttl;MGC94845;OTTHUMP00000020429;GSTO-1;OTTHUMP00000020430;OTTHUMP00000020431

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Chicken
  • Cynomolgus
  • Mouse
  • Zebrafish
  • E.coli
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • HEK293T
  • Mammalian cells
  • In Vitro Cell Free System
  • E. coli
  • GST
  • His
  • Non
  • His&T7
  • His&Fc&Avi
  • Myc&DDK
  • Flag
Cat.# Product name Source (Host) Species Tag Protein Length Price
GSTO1-3680H Recombinant Human GSTO1 protein, GST-tagged E.coli Human GST 1-241 aa
GSTO1-1995R Recombinant Rhesus monkey GSTO1 Protein, His-tagged Mammalian Cell Rhesus macaque His
GSTO1-28119TH Recombinant Human GSTO1, His-tagged E.coli Human His Full L. 1-241 a.a.
GSTO1-4424H Recombinant Human GSTO1 Protein, GST-tagged Wheat Germ Human GST
GSTO1-4789C Recombinant Chicken GSTO1 Mammalian Cell Chicken His
GSTO1-498H Recombinant Human Glutathione S-transferase Omega 1 E.coli Human Non
GSTO1-579C Recombinant Cynomolgus GSTO1 Protein, His-tagged Mammalian Cell Cynomolgus His
Gsto1-619M Recombinant Mouse Gsto1 protein, His & T7-tagged E.coli Mouse His&T7 Ile24~Pro233
GSTO1-7337M Recombinant Mouse GSTO1 Protein Mammalian Cell Mouse His
GSTO1-734Z Recombinant Zebrafish GSTO1 Mammalian Cell Zebrafish His
GSTO1-761HCL Recombinant Human GSTO1 cell lysate Human Non
GSTO1-1031H Recombinant Human GSTO1 Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
GSTO1-1031H-B Recombinant Human GSTO1 Protein Pre-coupled Magnetic Beads HEK293 Human
Gsto1-1070M Recombinant Mouse Gsto1 Protein, MYC/DDK-tagged HEK293T Mouse Myc&DDK
GSTO1-1351HFL Recombinant Full Length Human GSTO1 Protein, C-Flag-tagged Mammalian cells Human Flag Full L.
GSTO1-1816R Recombinant Rhesus Macaque GSTO1 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
GSTO1-1816R-B Recombinant Rhesus Macaque GSTO1 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
GSTO1-2459H Recombinant Human GSTO1 Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
GSTO1-30H Recombinant Human GSTO1 protein(Gly3~Gly240), His-tagged E.coli Human His Gly3~Gly240
GSTO1-325C Recombinant Cynomolgus Monkey GSTO1 Protein, His (Fc)-Avi-tagged HEK293 Cynomolgus His&Fc&Avi
GSTO1-325C-B Recombinant Cynomolgus Monkey GSTO1 Protein Pre-coupled Magnetic Beads HEK293 Cynomolgus
GSTO1-3365HF Recombinant Full Length Human GSTO1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 241 amino acids
GSTO1-3978M Recombinant Mouse GSTO1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
GSTO1-3978M-B Recombinant Mouse GSTO1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
GSTO1-8521H Recombinant Human GSTO1 protein, His-tagged E. coli Human His 256aa(including fusion tag)

    Involved Pathway

    GSTO1 involved in several pathways and played different roles in them. We selected most pathways GSTO1 participated on our site, such as Glutathione metabolism,Metabolism of xenobiotics by cytochrome P,Drug metabolism - cytochrome P, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSTO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of xenobiotics by cytochrome P DHDHL,MGST2,GSTM1,GSTA1,GSTM6,UGT2A3,UGT2B7,EPHX1,SULT2A1,UGT2A2
    Chemical carcinogenesis GSTT2B,CYP2A13,CYP3A5,ADH2-2,SULT1A1,CYP2C39,ADH1B,CYP3A43,GSTP2,GSTA4
    Glutathione metabolism MGST1,GPX6,GGCTB,GSTA4,GPX2,ODC1,GSTM3,GSTM7,GGCTA,GSS
    Drug metabolism - cytochrome P MGST1,GSTT2B,MGST2,GSTM,UGT1A7C,MGST1.2,GSTT1B,UGT2A1,AOX1,FMO4

    Protein Function

    GSTO1 has several biochemical functions, for example, glutathione dehydrogenase (ascorbate) activity,glutathione transferase activity,methylarsonate reductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GSTO1 itself. We selected most functions GSTO1 had, and list some proteins which have the same functions with GSTO1. You can find most of the proteins on our site.

    Function Related Protein
    oxidoreductase activity SCCPDHB,CYP2AA6,CYP2D26,AIFM3,HMGCRA,TDH,DEGS2,MOXD2,NOS2B,FADS1
    glutathione dehydrogenase (ascorbate) activity GSTO2
    methylarsonate reductase activity GSTO2
    protein binding NR2C1,FAM162A,KRT7,MOCS3,PPID,CASP10,ADRB1,TTC8,STX12,SOCS3
    glutathione transferase activity GSTA4,GSTT4,GSTT1,GRX2,GSTK1,MGST2,GSTM4,GSTZ1,EEF1E1,GSTA1

    Interacting Protein

    GSTO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSTO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSTO1.

    HSPB1;UBA5;TRAF6;EEF1G;SETDB1;RBM48;KAT5;CEP126;FN1

    Resources

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