GSC
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Official Full Name
goosecoid homeobox -
Overview
This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis. -
Synonyms
GSC;goosecoid homeobox;homeobox protein goosecoid
Recombinant Proteins
- Human
- Chicken
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GSC-13555H | Recombinant Human GSC, His-tagged | E.coli | Human | His | 1-257a.a. | |
| GSC-6883C | Recombinant Chicken GSC | Mammalian Cell | Chicken | His |
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| GSC-7302M | Recombinant Mouse GSC Protein | Mammalian Cell | Mouse | His |
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| GSC-8647Z | Recombinant Zebrafish GSC | Mammalian Cell | Zebrafish | His |
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| GSC-5728HCL | Recombinant Human GSC 293 Cell Lysate | HEK293 | Human | Non |
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| GSC-3950M | Recombinant Mouse GSC Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| GSC-3950M-B | Recombinant Mouse GSC Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| GSC-5387H | Recombinant Human GSC Protein, GST-tagged | Wheat Germ | Human | GST |
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| GSC-5617HF | Recombinant Full Length Human GSC Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 257 amino acids |
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Involved Pathway
GSC involved in several pathways and played different roles in them. We selected most pathways GSC participated on our site, such as Regulation of nuclear SMAD2/3 signaling,Regulation of retinoblastoma protein, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of nuclear SMAD2/3 signaling | SNIP1,CITED1,MYOD1,SKI,FOXH1,CBFB,NKX2 |
| Regulation of retinoblastoma protein | AATF,BRD2,BGLAP,SMARCB1,CKM,CBX4,ATF7,MYOD1,ELF1 |
Protein Function
GSC has several biochemical functions, for example, RNA polymerase II repressing transcription factor binding,RNA polymerase II transcription factor binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GSC itself. We selected most functions GSC had, and list some proteins which have the same functions with GSC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II transcription factor binding | T,PITX2,GATA6,WWP2,GATA1,ZFPM1,TOX2,GSK3B,SPOP,SMAD4 |
| sequence-specific DNA binding | MKXA,HNF4G,PAX6A,ZNF187,FOXE1,FOXF2,NKX2-4,PAX7,HOXC6B,HOXC12A |
| RNA polymerase II repressing transcription factor binding | GTF2A2,SP1,BBS2,HDAC2,MKKS,PROL1,DMAP1,BBS10,TTC8,STAT3 |
Interacting Protein
GSC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSC here. Most of them are supplied by our site. Hope this information will be useful for your research of GSC.
Resources
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References
- Bayin, NS; Modrek, AS; et al. Selective Lentiviral Gene Delivery to CD133-Expressing Human Glioblastoma Stem Cells. PLOS ONE 9:-(2014).
- Ivanov, VN; Hei, TK; et al. Radiation-induced glioblastoma signaling cascade regulates viability, apoptosis and differentiation of neural stem cells (NSC). APOPTOSIS 19:1736-1754(2014).
