GPR68
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Official Full Name
G protein-coupled receptor 68 -
Overview
Ovarian cancer G-protein coupled receptor 1 is a protein that in humans is encoded by the GPR68 gene. -
Synonyms
GPR68;G protein-coupled receptor 68;ovarian cancer G-protein coupled receptor 1;OGR1;G-protein coupled receptor 68;sphingosylphosphorylcholine receptor;ovarian cancer G protein-coupled receptor, 1;GPR12A;MGC111379;MGC156983
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GPR68-7201M | Recombinant Mouse GPR68 Protein | Mammalian Cell | Mouse | His |
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| GPR68-3889M | Recombinant Mouse GPR68 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| GPR68-3889M-B | Recombinant Mouse GPR68 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| RFL12909MF | Recombinant Full Length Mouse Ovarian Cancer G-Protein Coupled Receptor 1(Gpr68) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-365) |
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| RFL351BF | Recombinant Full Length Bovine Ovarian Cancer G-Protein Coupled Receptor 1(Gpr68) Protein, His-Tagged | E.coli expression system | Bovine | His | Full L. Full Length (1-361) |
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| RFL802HF | Recombinant Full Length Human Ovarian Cancer G-Protein Coupled Receptor 1(Gpr68) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-365) |
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Involved Pathway
GPR68 involved in several pathways and played different roles in them. We selected most pathways GPR68 participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (q) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR68 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Gastrin-CREB signalling pathway via PKC and MAPK | OPN4.1,OPN4A,DGKG,RGS19,GPR65,FPR-RS3,LPAR1,ANXA1A,GCGB,TRPC6A |
| GPCR downstream signaling | GPBAR1,OPN1LW1,DRD5,SCT,CXCR7B,OXGR1,SSTR2,ABHD6B,OXER1,NTS |
| Class A/1 (Rhodopsin-like receptors) | CHRM4,NMB,DRD5,TAC3,RLN2,CCL27,OXGR1,CYSLTR1,EDN2,CCR5 |
| GPCR ligand binding | QRFP,RAMP2,NPSR1,TAC1,NPS,NMBB,PYYA,EMR2,CCR3,RCA2.1 |
| G alpha (q) signalling events | CCK,GPR132B,LPAR1,KALRN,GPR4,ABHD12,UTS2,GPRC6A,NMBA,GPR132 |
| Signal Transduction | IRBP,PYYA,NTS,IFT88,LPAR2A,AKAP13,INTU,ARHGAP40,RNF146,TAS2R3 |
| GPCRs, Class A Rhodopsin-like | OR3A4P,SSTR5,CCRL2,DRD4,GPR171,CX3CR1,GPR31,CCR3,GPR17,DRD3 |
| Osteoclast Signaling | AIMP2 |
Protein Function
GPR68 has several biochemical functions, for example, G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR68 itself. We selected most functions GPR68 had, and list some proteins which have the same functions with GPR68. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled receptor activity | PTGER1C,NPFFR1L2,LPAR2B,TAS2R123,OLFR478,OLFCG1,VIPR2,TAAR14I,OLFR502,OLFR5 |
Interacting Protein
GPR68 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR68 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR68.
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References
- Yang, MH; Mailhot, G; et al. Expression of and role for ovarian cancer G-protein-coupled receptor 1 (OGR1) during osteoclastogenesis. JOURNAL OF BIOLOGICAL CHEMISTRY 281:23598-23605(2006).
