GPR65
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Official Full Name
G protein-coupled receptor 65 -
Overview
Psychosine receptor is a protein that in humans is encoded by the GPR65 gene. -
Synonyms
GPR65;G protein-coupled receptor 65;psychosine receptor;hTDAG8;TDAG8;G-protein coupled receptor 65;T-cell death-associated gene 8 protein
Recombinant Proteins
- Rhesus macaque
- Human
- Mouse
- Mus musculus
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- E.coli
- His
- His&Fc&Avi
- Avi&His&Fc
- Non
- GST
Involved Pathway
GPR65 involved in several pathways and played different roles in them. We selected most pathways GPR65 participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (q) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR65 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Gastrin-CREB signalling pathway via PKC and MAPK | GCGA,DGKG,ANXA1A,DGKB,EDNRAB,CASR,KISS1,EDN2,MLN,LPAR2B |
| GPCR ligand binding | RLN3,TAS2R16,RAMP2,OXGR1A.3,CCR7,DRD4,EMR2,SST1.1,OXGR1A.2,S1PR5B |
| GPCR downstream signaling | NMBA,ADRA2B,PTGDR2,EDNRA,TRPC7,SST,APPB,ITSN1,RGS21,CCR8 |
| Class A/1 (Rhodopsin-like receptors) | ADRa1A,PTGDR2,CCL35.1,CX3CR1,NPFF,PROKR1,CXCR7B,GPR18,CCR6,GPR132 |
| Signaling by GPCR | FGD4A,RCA2.1,PROK1,EMR3,SOUL4,ARHGEF16,ARHGEF18A,SCT,APLN,OR7D2 |
| G alpha (q) signalling events | FPR-RS4,GPR132,TRPC3,OPN4A,GRP,NMU,CHRM3,CASR,EDNRB,TRPC6A |
| GPCRs, Class A Rhodopsin-like | CCR3,GPR17,FPR-RS3,LTB4R,GPR4,CCR9,GPR18,FPR-RS4,RRH,OPN1MW2 |
| Signal Transduction | PTHLH,GPR4,QRFP,GPBAR1,RDH7,CHRDL1,FGD4,RLN2,ARHGAP26,NEDD8 |
Protein Function
GPR65 has several biochemical functions, for example, G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR65 itself. We selected most functions GPR65 had, and list some proteins which have the same functions with GPR65. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled receptor activity | VMN1R54,OR3A2,PROKR1A,TAAR14L,OR51B2,MRGPRB3,GPR81,MAS1,CHRM2A,GRM4 |
Interacting Protein
GPR65 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR65 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR65.
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References
- Onozawa, Y; Fujita, Y; et al. Activation of T cell death-associated gene 8 regulates the cytokine production of T cells and macrophages in vitro. EUROPEAN JOURNAL OF PHARMACOLOGY 683:325-331(2012).
