GPR126
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Official Full Name
G protein-coupled receptor 126 -
Overview
This gene, which is upregulated in human umbilical vein endothelial cells, encodes a G protein-coupled receptor. Variations in this gene can affect a persons stature. Multiple transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Mar 2009] -
Synonyms
GPR126;G protein-coupled receptor 126;APG1;DREG;VIGR;PS1TP2;G-protein coupled receptor 126;HBV PreS1-transactivated protein 2;vascular inducible G protein-coupled receptor;vascular-inducible G protein-coupled receptor;developmentally regulated G-protein-coupled receptor
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GPR126-2750C | Recombinant Chicken GPR126 | Mammalian Cell | Chicken | His |
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| GPR126-7137M | Recombinant Mouse GPR126 Protein | Mammalian Cell | Mouse | His |
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| GPR126-7546Z | Recombinant Zebrafish GPR126 | Mammalian Cell | Zebrafish | His |
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| GPR126-3846M | Recombinant Mouse GPR126 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| GPR126-3846M-B | Recombinant Mouse GPR126 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
GPR126 involved in several pathways and played different roles in them. We selected most pathways GPR126 participated on our site, such as Odorant GPCRs, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR126 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Odorant GPCRs | LGR4,VMN1R43,VMN1R48,GPR158,GPR31B,VMN1R40,GPR173,MRGPRG,WLS,VMN1R46 |
Protein Function
GPR126 has several biochemical functions, for example, G-protein coupled receptor activity,signal transducer activity,transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR126 itself. We selected most functions GPR126 had, and list some proteins which have the same functions with GPR126. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| signal transducer activity | F2RL2,TAAR13E,GNG5,CD40,GPR183B,TAAR12C,OPRD1A,GNA11B,GNG12A,LPAR6 |
| transmembrane signaling receptor activity | OR115-6,LILRA1,CALCRLA,OR4C12,SLC22A17,IL27RA,MRC1,OR4D6,SPN,Cd79a |
| G-protein coupled receptor activity | TAS2R123,OLFR15,OR5B2,OR10H1,GPR32,NPY8BR,MRGPRH,GPR114,GHRHRA,APLNR |
Interacting Protein
GPR126 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR126 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR126.
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References
- Hamann, J; Aust, G; et al. International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein-Coupled Receptors. PHARMACOLOGICAL REVIEWS 67:338-367(2015).
- Petersen, SC; Luo, R; et al. The Adhesion GPCR GPR126 Has Distinct, Domain-Dependent Functions in Schwann Cell Development Mediated by Interaction with Laminin-211. NEURON 85:755-769(2015).
