GPR124
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Official Full Name
G protein-coupled receptor 124 -
Overview
Probable G-protein coupled receptor 124 is a protein that in humans is encoded by the GPR124 gene. -
Synonyms
GPR124;G protein-coupled receptor 124;G-protein coupled receptor 124;DKFZp434C211;DKFZp434J0911;FLJ14390;KIAA1531;TEM5;tumor endothelial marker 5
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GPR124-7135M | Recombinant Mouse GPR124 Protein | Mammalian Cell | Mouse | His |
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| GPR124-3844M | Recombinant Mouse GPR124 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| GPR124-3844M-B | Recombinant Mouse GPR124 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
GPR124 involved in several pathways and played different roles in them. We selected most pathways GPR124 participated on our site, such as Odorant GPCRs, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR124 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Odorant GPCRs | GPR126,MRGPRB8,VMN1R48,GPR152,MRGPRB2,GPR108,GPR158,GPR27,GPR139,WLS |
Protein Function
GPR124 has several biochemical functions, for example, G-protein coupled receptor activity,signal transducer activity,transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR124 itself. We selected most functions GPR124 had, and list some proteins which have the same functions with GPR124. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transmembrane signaling receptor activity | KLRF1,SLC22A17,TLR6,LAG3,LILRA1,OR4C13,GIPR,CELSR1,OR2A4,VIPR1B |
| signal transducer activity | TAS2R114,LITAF,CXCR4A,ADRB2A,GNG13B,TAAR14A,TRHR2,GPR34L,GNG13,PTK2 |
| G-protein coupled receptor activity | RXFP3,NMUR1,GPR34A,OPN1MW3,OR2L2,S1PR1,DRD2L,MTNR1BA,OR12D2,VIPR2 |
Interacting Protein
GPR124 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR124 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR124.
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References
- Hamann, J; Aust, G; et al. International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein-Coupled Receptors. PHARMACOLOGICAL REVIEWS 67:338-367(2015).
- Posokhova, E; Shukla, A; et al. GPR124 Functions as a WNT7-Specific Coactivator of Canonical beta-Catenin Signaling. CELL REPORTS 10:123-130(2015).
