GPR120

  • Official Full Name

    O3FAR1 omega-3 fatty acid receptor 1
  • Overview

    This gene encodes a G protein-coupled receptor (GPR) which belongs to the rhodopsin family of GPRs. The encoded protein;functions as a receptor for free fatty acids, including omega-3, and participates in suppressing anti-inflammatory;responses and insulin sensitizing. Multiple transcript variants encoding different isoforms have been found for this;gene.
  • Synonyms

    GT01;PGR4;GPR120;GPR129;MGC119984;DKFZp686F0824;omega-3 fatty acid receptor 1;OTTHUMP00000032309;OTTHUMP00000032310;G protein-coupled receptor 120;G protein-coupled receptor 129;G-protein coupled receptor 120;G-protein coupled receptor 129;G protein-coupled receptor PGR4;G-protein coupled receptor GT01;G-protein coupled receptor PGR4;G-protein-coupled receptor GT01
Cat.# Product name Source (Host) Species Tag Protein Length Price
GPR120-5799HCL Recombinant Human GPR120 293 Cell Lysate HEK293 Human Non

    Involved Pathway

    GPR120 involved in several pathways and played different roles in them. We selected most pathways GPR120 participated on our site, such as Class A/1 (Rhodopsin-like receptors),Free fatty acid receptors,GPCR ligand binding, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR120 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Signaling by GPCR RLN2,TAS2R3,CCBP2,PLEKHG2,EMR4,GPRC6A,GPR31B,FGD2,HEBP1,GPR55A
    Incretin synthesis, secretion, and inactivation GRP,CDX2,O3far1,DPP4,PCSK1,SPCS3,GPR119,SLC38A8
    Metabolism of proteins GALNTL2,SCMH1,TPP1,YY2,APCS,KCNA6,NEU4,SPON1B,PPP6R1,SPON1A
    Free fatty acid receptors GPR31,FFAR3,GPR31B
    Signal Transduction KIF14,CD97,ARHGAP33,NPHP4,NOTUM,JUPA,FABP11A,CCL35.1,OR52B4,RGS17
    Class A/1 (Rhodopsin-like receptors) TAC2,CCR1,OXGR1A.3,CX3CR1,GPR37B,GRP,CXCL11.8,RGS1,CCL35.1,OPN5
    Peptide hormone metabolism BCHE,INHA,ATP6AP2,RAB27A,SLC30A8,SLC30A5,ACE,GRP,CGB5,SLC38A8
    GPCR ligand binding CALCA,GPR37L1,CNR2,PTGDR2,GPR31,PPY,TRH,EMR1,CXCL13,GCGA

    Protein Function

    GPR120 has several biochemical functions, for example, fatty acid binding,NOT peptide binding,taste receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR120 itself. We selected most functions GPR120 had, and list some proteins which have the same functions with GPR120. You can find most of the proteins on our site.

    Function Related Protein
    taste receptor activity TAS2R13,TAS2R140,TAS2R143,TAS2R7,TAS1R2,TAS2R144,TAS2R136,TAS2R137,TAS2R3,TAS2R134
    fatty acid binding APOC1,FABP1,NDUFAB1,PMP2,FABP1A,FABP10A,ADH5,LBFABP,O3far1,Alb

    Interacting Protein

    GPR120 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPR120 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPR120.

    Resources

    References

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