GPN3
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Official Full Name
GPN-loop GTPase 3 -
Overview
GPN-loop GTPase 3 is an enzyme that in humans is encoded by the GPN3 gene. -
Synonyms
GPN3;GPN-loop GTPase 3;ATP binding domain 1 family, member C , ATPBD1C;MGC14560;ATP-binding domain 1 family member C;ATPBD1C;protein x 0004;ATP binding domain 1 family, member C
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Mouse
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ATPBD1C-1023H | Recombinant Human ATPBD1C protein, GST-tagged | Wheat Germ | Human | GST |
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| GPN3-1758Z | Recombinant Zebrafish GPN3 | Mammalian Cell | Zebrafish | His |
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| GPN3-2644R | Recombinant Rat GPN3 Protein | Mammalian Cell | Rat | His |
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| GPN3-7120M | Recombinant Mouse GPN3 Protein | Mammalian Cell | Mouse | His |
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| GPN3-5801HCL | Recombinant Human GPN3 293 Cell Lysate | HEK293 | Human | Non |
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| GPN3-1274HF | Recombinant Full Length Human GPN3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 284 amino acids |
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| GPN3-2298R | Recombinant Rat GPN3 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| GPN3-2298R-B | Recombinant Rat GPN3 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| GPN3-3836M | Recombinant Mouse GPN3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| GPN3-3836M-B | Recombinant Mouse GPN3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
GPN3 involved in several pathways and played different roles in them. We selected most pathways GPN3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GPN3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
GPN3 has several biochemical functions, for example, GTP binding,hydrolase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GPN3 itself. We selected most functions GPN3 had, and list some proteins which have the same functions with GPN3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | DCTN4,CHP,PGBD1,CBR2,NPBWR2,PSKH1,LRCH4,CRP,TBX5,Arid4b |
| GTP binding | ARL4CA,GNAO1,GNAV1,RHOBTB1,GNAIA,EHD3,RAB6C,EIF2S3,ARL4A,GNA14 |
| hydrolase activity | HTRA1A,USP9,ATP9B,CLCA5,CDC14A,NUDT22,Amy1,ACTG2,ACP5B,Ces2c |
Interacting Protein
GPN3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPN3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPN3.
GPN1;WDR48;MED26;SLX4;MED9
Resources
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References
- Mendez-Hernandez, LE; Perez-Mejia, AE; et al. Gpn1 and Gpn3 associate tightly and their protein levels are mutually dependent in mammalian cells. FEBS LETTERS 588:3823-3829(2014).
- Minaker, SW; Filiatrault, MC; et al. Biogenesis of RNA Polymerases II and III Requires the Conserved GPN Small GTPases in Saccharomyces cerevisiae. GENETICS 193:853-U305(2013).
- Calera, MR; Zamora-Ramos, C; et al. Parcs/Gpn3 is required for the nuclear accumulation of RNA polymerase II. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1813:1708-1716(2011).
- Carre, C; Shiekhattar, R; et al. Human GTPases Associate with RNA Polymerase II To Mediate Its Nuclear Import. MOLECULAR AND CELLULAR BIOLOGY 31:3953-3962(2011).
