GOLGA5
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Official Full Name
golgin A5 -
Overview
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein is a coiled-coil membrane protein that has been postulated to play a role in vesicle tethering and docking. Translocations involving this gene and the ret proto-oncogene have been found in tumor tissues; the chimeric sequences have been designated RET-II and PTC5. -
Synonyms
GOLGA5;golgin A5;golgi autoantigen, golgin subfamily a, 5;Golgin subfamily A member 5;golgi integral membrane protein 5;golgin 84;GOLIM5;ret II;rfg5;Cell proliferation inducing gene 31;Cell proliferation-inducing gene 31 protein;GOGA5_HUMAN;GOLGA 5;Golgi autoantigen golgin subfamily a 5;Golgin-84;Golgin84;GOLIM 5;Protein Ret-II;PTC5;Ret fused gene 5;RET fused gene 5 protein;Ret II protein;RET-fused gene 5 protein;RFG 5;OTTHUMP00000245464;ret-II
Recombinant Proteins
- Zebrafish
- Rhesus macaque
- Rat
- Mouse
- Human
- Mammalian Cells
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- GST
Involved Pathway
GOLGA5 involved in several pathways and played different roles in them. We selected most pathways GOLGA5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GOLGA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
GOLGA5 has several biochemical functions, for example, Rab GTPase binding,protein binding, bridging,protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GOLGA5 itself. We selected most functions GOLGA5 had, and list some proteins which have the same functions with GOLGA5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| Rab GTPase binding | MICALL2,STXBP5L,TBC1D20,RHOBTB3,EXPH5,RAB11FIP4A,ALS2,GDI1,NSF,RPH3A |
| protein homodimerization activity | JUP,BCL11A,TOX3,S100A10,HAND1,IMPA1,NACC2,EPHX2,CHMP4C,CEBPB |
| protein binding, bridging | STUB1,NCK1,FBXW7,SYNM,LOR,CUX1,CRADD,FSCN2B,MMS19,PPP4R2 |
Interacting Protein
GOLGA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GOLGA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of GOLGA5.
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References
- Zhu, HL; Li, HM; et al. Persistent and acute chlamydial infections induce different structural changes in the Golgi apparatus. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY 304:577-585(2014).
- Shahheydari, H; Frost, S; et al. Identification of PLP2 and RAB5C as novel TPD52 binding partners through yeast two-hybrid screening. MOLECULAR BIOLOGY REPORTS 41:4565-4572(2014).
