GNL2
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Official Full Name
guanine nucleotide binding protein-like 2 (nucleolar) -
Overview
Nucleolar GTP-binding protein 2 is a protein that in humans is encoded by the GNL2 gene. -
Synonyms
GNL2;guanine nucleotide binding protein-like 2 (nucleolar);nucleolar GTP-binding protein 2;HUMAUANTIG;Ngp 1;Autoantigen NGP1;DJ423B22.6 (novel nucleolar guanosine 5-triphosphate binding protein;FLJ40906;NGP1;Nucleolar GTP binding protein 2;Nucleolar GTPase;autoantigen NGP-1;nucleolar G-protein gene 1;novel nucleolar guanosine 5-triphosphate binding protein autoantigen;Ngp-1
Recombinant Proteins
- Zebrafish
- Human
- Mammalian Cell
- E.coli
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&SUMO
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GNL2-12427Z | Recombinant Zebrafish GNL2 | Mammalian Cell | Zebrafish | His |
|
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| GNL2-28149TH | Recombinant Human GNL2, His-tagged | E.coli | Human | His | 181-731 a.a. |
|
| GNL2-723HCL | Recombinant Human GNL2 cell lysate | Human | Non |
|
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| GNL2-2861H | Recombinant Human GNL2 protein(441-700 aa), C-His-tagged | E.coli | Human | His | 441-700 aa |
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| GNL2-2862H | Recombinant Human GNL2 protein(551-700 aa), C-His-tagged | E.coli | Human | His | 551-700 aa |
|
| GNL2-4403H | Recombinant Human GNL2 protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 1-731aa |
|
| GNL2-5080H | Recombinant Human GNL2 Protein, GST-tagged | Wheat Germ | Human | GST |
|
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| GNL2-5396HF | Recombinant Full Length Human GNL2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 731 amino acids |
|
Involved Pathway
GNL2 involved in several pathways and played different roles in them. We selected most pathways GNL2 participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome biogenesis in eukaryotes | RIOK1,NOP10,FBL,NHP2L1A,PWP2H,RRP7A,cka1,NHP2,LSG1,EMG1 |
Protein Function
GNL2 has several biochemical functions, for example, GTP binding,GTPase activity,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNL2 itself. We selected most functions GNL2 had, and list some proteins which have the same functions with GNL2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activity | TUBA8,RALAA,RAB17,GNA13A,TUBAL3,RAB34A,HBS1L,EEF1A2,RAB25A,RAB5AA |
| GTP binding | SAR1B,ARF4,EIF5,NKIRAS1,EHD2,RND1,RAB7,SEPT10,TUBB2A,SCG5 |
| poly(A) RNA binding | TIAL1,LRPPRC,RG9MTD1,ZFP768,ZCCHC6,DZIP3,PTCD2,DDX47,RPUSD3,IGF2BP1 |
Interacting Protein
GNL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNL2.
FOS;MDM2;G3BP1;LYAR;DDX56;USP36;G3BP2;ssrna_ug;Srp72;ESR1;NPM1;Eif3a;RPL10;MNDA;HNRNPU;IFI16;ESR2
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References
- Casadio, A; Longman, D; et al. Identification and characterization of novel factors that act in the nonsense-mediated mRNA decay pathway in nematodes, flies and mammals. EMBO REPORTS 16:71-78(2015).
- Essers, PB; Pereboom, TC; et al. A comparative study of nucleostemin family members in zebrafish reveals specific roles in ribosome biogenesis.. DEVELOPMENTAL BIOLOGY 385:304-315(2014).
