GNB3
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Official Full Name
guanine nucleotide binding protein (G protein), beta polypeptide 3 -
Overview
G-Protein b3 (GNB3) is a guanine nucleotide-binding protein (G protein). G-proteins are involved as a modulator or transducer in various transmembrane signaling systems. -
Synonyms
GNB3;guanine nucleotide binding protein (G protein), beta polypeptide 3;guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3;transducin beta chain 3;G protein, beta-3 subunit;hypertension associated protein;GTP-binding regulatory protein
Recombinant Proteins
- Rhesus macaque
- Rat
- Human
- Mammalian Cells
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- GST
Involved Pathway
GNB3 involved in several pathways and played different roles in them. We selected most pathways GNB3 participated on our site, such as Ras signaling pathway,Chemokine signaling pathway,PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glutamatergic synapse | GRM5,GRIN3B,PPP3R2,GNAQ,GRIA3,SHANK3,SLC17A7,SLC38A2,GRM2,GRM6 |
| Circadian entrainment | CAMK2G,CACNA1G,CALM1,MAPK3,GNG13,GNG2,GRIA3,MTNR1A,GNG12,KCNJ6 |
| PIK-Akt signaling pathway | PIK3CB,NOS3,VWF,ITGA2,GH2,FN1,G6PC2,FLT1,FOXO3,PHLPP2 |
| Dopaminergic synapse | GNG7,GNG13,MAOB,PPP1CC,CAMK2G,DDC,GRIA1,GNB4,PPP3CA,GNG2 |
| Taste transduction | PRKACA,TAS2R121,TAS2R118,TAS2R117,ITPR3,TAS2R116,TAS2R137,GNAS,GNG13,TAS1R2 |
| Serotonergic synapse | KRAS,PLA2G4F,HTR5A,CYP2C70,CYP2C39,GNG10,CYP2D9,GNG12,PLA2G4C,GNG3 |
| GABAergic synapse | GABRD,GLS,GABRG1,GNB1,GABRA5,PRKACA,GNG11,GABRB3,GABRG3,SLC12A5 |
| Retrograde endocannabinoid signaling | PRKACG,MAPK12,GRIA1,GABRB2,GNAQ,MAPK9,GABRA2,GABRG2,SLC17A7,SLC17A6 |
| Alcoholism | GM14479,HIST2H2BB,GNGT1,HDAC1,H2AFJ,SHC4,PPP1CC,HIST1H2AG,HIST1H2BB,CALML5 |
Protein Function
GNB3 has several biochemical functions, for example, GTPase activity,GTPase binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNB3 itself. We selected most functions GNB3 had, and list some proteins which have the same functions with GNB3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | NOV,HHLA3,CAMSAP1L1,CHAC1,BRPF3,ALKBH4,DKK1B,TRIM23,ACTN1,RBM23 |
| GTPase binding | SPTBN1,GOLGA4,IARS,RASA1,RAB3D,HSP90AA1,VPS41,SH3GL1,PTPRN,YBX1 |
| GTPase activity | ARFRP1,RAB3DA,RAB3D,EEF2B,ARF3,GBP3,RAB31,RAB35,RRAGCA,MFN1B |
| signal transducer activity | TSPAN6,PTGER1C,OLFR474,OLFR1002,STAT1A,GNG13B,OLFR147,GPR34L,OLFCG5,OLFR1440 |
Interacting Protein
GNB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNB3.
CXCR5;NS;ERBB2;P;ESR2;CDC5L
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