GIMAP4
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Official Full Name
GTPase, IMAP family member 4 -
Overview
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The encoded protein of this gene may be negatively regulated by T-cell acute lymphocytic leukemia 1 (TAL1). In humans, the IAN subfamily genes are located in a cluster at 7q36.1. -
Synonyms
GIMAP4;GTPase, IMAP family member 4;GTPase IMAP family member 4;FLJ11110;HIMAP4;IMAP4;hIAN1;IAN1;Immunity associated nucleotide 1 protein;Immunity associated protein 4;MSTP062;IAN-1;immunity-associated protein 4;human immune associated nucleotide 1;immunity-associated nucleotide 1 protein
Recombinant Proteins
- Human
- Rhesus macaque
- Cynomolgus
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
GIMAP4 involved in several pathways and played different roles in them. We selected most pathways GIMAP4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GIMAP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
GIMAP4 has several biochemical functions, for example, GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GIMAP4 itself. We selected most functions GIMAP4 had, and list some proteins which have the same functions with GIMAP4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | RERGLA,RAB1,GBP4,GMPPAA,GNAT1,ARL4AB,MTG1,GNAIA,RHOH,RHOJ |
Interacting Protein
GIMAP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GIMAP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GIMAP4.
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References
- Carmona, FD; Martin, J; et al. Genetics of vasculitis. CURRENT OPINION IN RHEUMATOLOGY 27:10-17(2015).
- Heinonen, MT; Kanduri, K; et al. Tubulin- and actin-associating GIMAP4 is required for IFN-gamma secretion during Th cell differentiation. IMMUNOLOGY AND CELL BIOLOGY 93:158-166(2015).
