GIMAP1
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Official Full Name
GTPase, IMAP family member 1 -
Overview
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene is thought to be involved in the differentiation of T helper (Th) cells of the Th1 lineage, and the related mouse gene has been shown to be critical for the development of mature B and T lymphocytes. Read-through transcription exists between this gene and the downstream GIMAP5 (GTPase, IMAP family member 5) gene. -
Synonyms
GIMAP1;GTPase, IMAP family member 1;GTPase IMAP family member 1;HIMAP1;IMAP1;IMAP38;immunity associated protein 1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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| GIMAP1-5939HCL | Recombinant Human GIMAP1 293 Cell Lysate | HEK293 | Human | Non |
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| GIMAP1-2908H | Recombinant Human GIMAP1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Gimap1-3207M | Recombinant Mouse Gimap1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| RFL34807MF | Recombinant Full Length Mouse Gtpase Imap Family Member 1(Gimap1) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-277) |
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Involved Pathway
GIMAP1 involved in several pathways and played different roles in them. We selected most pathways GIMAP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GIMAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
GIMAP1 has several biochemical functions, for example, GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GIMAP1 itself. We selected most functions GIMAP1 had, and list some proteins which have the same functions with GIMAP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | ASCL1B,RAB1BB,RHOB,TUBB6,MFHAS1,SEPT6,TUBB2B,SRPR,RAB27B,RAB36 |
Interacting Protein
GIMAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GIMAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GIMAP1.
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References
- Webb, LMC; Bell, SE; et al. Critical role for GIMAP1 in the germinal centre reaction. IMMUNOLOGY 143:66-66(2014).
- Webb, LMC; Pascall, JC; et al. Generation and Characterisation of Mice Deficient in the Multi-GTPase Domain Containing Protein, GIMAP8. PLOS ONE 9:-(2014).
