GGT7
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Official Full Name
gamma-glutamyltransferase 7 -
Overview
This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. -
Synonyms
GGT7;gamma-glutamyltransferase 7;gamma glutamyltransferase like 3 , GGTL3, GGTL5;D20S101;dJ18C9.2;GGT 7;glutathione hydrolase 7;gamma-glutamyltransferase 4;gamma-glutamyltranspeptidase 7;gamma-glutamyltransferase-like 3;gamma-glutamyltransferase
Recombinant Proteins
- Rhesus macaque
- Rat
- Mouse
- Mammalian Cells
- HEK293
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GGT7-1841R | Recombinant Rhesus monkey GGT7 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| GGT7-2525R | Recombinant Rat GGT7 Protein | Mammalian Cells | Rat | His |
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| GGT7-6334M | Recombinant Mouse GGT7 Protein | Mammalian Cells | Mouse | His |
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| GGT7-1662R | Recombinant Rhesus Macaque GGT7 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| GGT7-1662R-B | Recombinant Rhesus Macaque GGT7 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| GGT7-2181R | Recombinant Rat GGT7 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| GGT7-2181R-B | Recombinant Rat GGT7 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| GGT7-3546M | Recombinant Mouse GGT7 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| GGT7-3546M-B | Recombinant Mouse GGT7 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
GGT7 involved in several pathways and played different roles in them. We selected most pathways GGT7 participated on our site, such as Taurine and hypotaurine metabolism,Cyanoamino acid metabolism,Glutathione metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with GGT7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | CCBL1,AGPS,TUSC3,B3GNT3,PPCDC,NDUFS8A,NME2,PYCRL,NDUFA4L,TYMP |
| Glutathione metabolism | GPX5,GGCTB,GPX3,GSTT2,GGT1A,GGT1,GPX4B,GSTM3,GSTP2,OPLAH |
| Cyanoamino acid metabolism | GBA3,GGT1,SHMT1,SHMT2,GGT5,GGT6,GGT5A,GGT1A |
| Taurine and hypotaurine metabolism | GAD1,ADO,CDO1,GGT5A,CSAD,GAD2,GGT1A,GAD1B,ADOB,GGT1 |
Protein Function
GGT7 has several biochemical functions, for example, gamma-glutamyltransferase activity,glutathione hydrolase activity,hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GGT7 itself. We selected most functions GGT7 had, and list some proteins which have the same functions with GGT7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| gamma-glutamyltransferase activity | GGT5,GGT6,GGT5A,GGT1A,GGTLC1,GGT1 |
| hydrolase activity | MMP25,IHHB,PSMC1A,ATP2B3A,PPP3CCB,ACP5B,ATP11A,ACOT5,IHHA,EIF4A1A |
| glutathione hydrolase activity | GGT5,GGT1,GGT6 |
| transferase activity | GALNT11,NADKD1,SPTLC2A,ELOVL6L,COQ2,SULT3ST3,CRATB,ELOVL4,EXT1A,ELOVL4A |
| molecular_function | YDJC,MARCH11,SH3RF3,STRA6L,VMN1R95,SERF1A,TMEM50B,TP53TG1,V1RD19,KIAA0247 |
| transferase activity, transferring acyl groups | TMEM68,ZDHHC6,LRAT,ZDHHC16A,MBOAT2,ZDHHC24,AANAT1,CHATB,ACAA1A,ZDHHC3B |
Interacting Protein
GGT7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GGT7 here. Most of them are supplied by our site. Hope this information will be useful for your research of GGT7.
Ywhae
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References
- Ruhl, CE; Menke, A; et al. Relationship of Hepatitis C Virus Infection With Diabetes in the US Population. HEPATOLOGY 60:1139-1149(2014).
- Schmidt, CS; Schon, D; et al. Viral Hepatitis in Alcohol-Dependent Inpatients Prevalence, Risk Factors, and Treatment Uptake. JOURNAL OF ADDICTION MEDICINE 7:417-421(2013).
