GCSF
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Official Full Name
Granulocyte colony-stimulating factor -
Overview
Granulocyte colony-stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream. Functionally, it is a cytokine and hormone, a type of colony-stimulating factor, and is produced by a number of different tissues. G-CSF also stimulates the survival, proliferation, differentiation, and function of neutrophil precursors and mature neutrophils. G-CSF regulates them using Janus kinase (JAK)/signal transducer and activator of transcription (STAT) and Ras/mitogen-activated protein kinase (MAPK) and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signal transduction pathway. -
Synonyms
Granulocyte colony-stimulating factor;G-CSF;GCSF
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GCSF-001A | GCSF Purification Resin | Non |
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| GCSF-3277R | Recombinant Rat GCSF protein, His-tagged | HEK293 | Rat | His | Ile22~Leu198 |
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| GCSF-3373M | Recombinant Mouse GCSF protein, His-tagged | HEK293 | Mouse | His | Glu55~His206 |
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Involved Pathway
GCSF involved in several pathways and played different roles in them. We selected most pathways GCSF participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GCSF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
GCSF has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by GCSF itself. We selected most functions GCSF had, and list some proteins which have the same functions with GCSF. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
GCSF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GCSF here. Most of them are supplied by our site. Hope this information will be useful for your research of GCSF.
Resources
Research Area
Angiogenic ActivatorColony-Stimulating Factor (CSF)
IL-6 Family Ligands
Angiogenic Activator in Cancer
Related Services
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References
