GANAB
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Official Full Name
glucosidase, alpha; neutral AB -
Overview
Neutral alpha-glucosidase AB is an enzyme that in humans is encoded by the GANAB gene. -
Synonyms
GANAB;glucosidase, alpha;neutral AB;neutral alpha-glucosidase AB;G2AN;GluII;KIAA0088;alpha-glucosidase 2;glucosidase II subunit alpha;alpha glucosidase II alpha subunit;GLUII
Recombinant Proteins
- Human
- Rhesus macaque
- Cynomolgus
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- His&T7
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
GANAB involved in several pathways and played different roles in them. We selected most pathways GANAB participated on our site, such as N-Glycan biosynthesis,Metabolic pathways,Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with GANAB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | UROC1,NOS2B,GALNT1,PIGV,GKUP,ACSM3,CYP2C18,ADH1,CYP24A1,ACSM2B |
| Protein processing in endoplasmic reticulum | RRBP1,LMAN1,RAD23AA,HSP90B1,UBE2E1,UGGT2,DNAJB1B,DNAJC5B,PDIA3,HSP70 |
| N-Glycan biosynthesis | TUSC3,MGAT1B,MGAT3,ZNF408,MAN1A2,ALG12,B4GALT2,FUT8A,RPN2,DPM1 |
Protein Function
GANAB has several biochemical functions, for example, carbohydrate binding,glucan 1,3-alpha-glucosidase activity,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GANAB itself. We selected most functions GANAB had, and list some proteins which have the same functions with GANAB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | DDX55,LARP4,CSTF2T,CANX,FAM103A1,AASS,RPL21,MSI1,MBNL3,PPIG |
| carbohydrate binding | PKD1L3,SIGLEC9,CLEC2G,PRG2,CLEC2D,LMAN2,LGALS7B,Fcer2a,CLEC1B,ASGR2 |
Interacting Protein
GANAB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GANAB here. Most of them are supplied by our site. Hope this information will be useful for your research of GANAB.
MYC;env;env;4505953;SGK1;GBAS;TIMP2;TFE3;VDAC1;MCC;HLA-B;HLA-C;EIF6;ARF6;CCNA1
Resources
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References
- Park, JS; Kim, HG; et al. Effect of enzyme replacement therapy in late onset Pompe disease: open pilot study of 48 weeks follow-up. NEUROLOGICAL SCIENCES 36:599-605(2015).
- van Gelder, CM; Hoogeveen-Westerveld, M; et al. Enzyme therapy and immune response in relation to CRIM status: the Dutch experience in classic infantile Pompe disease. JOURNAL OF INHERITED METABOLIC DISEASE 38:305-314(2015).
