GABRP
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Official Full Name
gamma-aminobutyric acid (GABA) A receptor, pi -
Synonyms
GABRP;gamma-aminobutyric acid (GABA) A receptor, pi;gamma-aminobutyric acid receptor subunit pi;GABA(A) receptor subunit pi;Gamma aminobutyric acid (GABA) A receptor pi;Gamma aminobutyric acid A receptor pi;Gamma aminobutyric acid receptor pi subunit;Gamma aminobutyric acid receptor subunit pi;GBRP_HUMAN;MGC126386;MGC126387;gamma-aminobutyric acid (GABA-A) receptor, pi
Recombinant Proteins
- Rat
- Mouse
- Human
- Mammalian Cell
- E.coli
- HEK293
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| GABRP-2455R | Recombinant Rat GABRP Protein | Mammalian Cell | Rat | His |
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| GABRP-6157M | Recombinant Mouse GABRP Protein | Mammalian Cell | Mouse | His |
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| GABRP-1361H | Recombinant Human GABRP protein, His-tagged | E.coli | Human | His | 17-242aa |
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| GABRP-2111R | Recombinant Rat GABRP Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| GABRP-2111R-B | Recombinant Rat GABRP Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| GABRP-3436M | Recombinant Mouse GABRP Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| GABRP-3436M-B | Recombinant Mouse GABRP Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
GABRP involved in several pathways and played different roles in them. We selected most pathways GABRP participated on our site, such as Neuroactive ligand-receptor interaction,Retrograde endocannabinoid signaling,GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GABRP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Nicotine addiction | GRIA1,GRIA2,GRIA3,GABRA4,GABRB1,GRIN2C,GRIN2D,GABRG3,GABRE,GABRA6 |
| Retrograde endocannabinoid signaling | ABHD6,GABRD,PLCB4,GABRR2,GRM5,GABRA2,SLC17A6,GABRB3,GNG3,ITPR1 |
| Neuroactive ligand-receptor interaction | PTGER1,NPFFR1L2,MCHR1,CHRNB3A,GHRA,GHRHRL,AGTR1B,TAAR14D,NPFFR2.1,ADRB2B |
| GABAergic synapse | GNAO1,HAP1,GABRB2,PRKCA,GNG2,SLC38A3,GAD2,GABRA2,GABRQ,PRKCB |
Protein Function
GABRP has several biochemical functions, for example, contributes_to GABA-A receptor activity,chloride channel activity,extracellular ligand-gated ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GABRP itself. We selected most functions GABRP had, and list some proteins which have the same functions with GABRP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chloride channel activity | CLIC6,GABRG1,GABRE,APOL1,CLCN5,CLCA2,CFTR,SLC26A11,CLIC5A,GABRG2 |
| extracellular ligand-gated ion channel activity | Chrng,GABRR3A,CHRNB1L,CHRNB3B,CHRNA10A,GABRZ,CHRNB3A,GABRR2A,SIX2A,GLRBB |
| contributes_to GABA-A receptor activity | GABRA3,GABRR2A,GABRA6A,GABRZ,GABRA2,GABRA6,GABRA4,GABRG2,GABRG3,GABRQ |
Interacting Protein
GABRP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GABRP here. Most of them are supplied by our site. Hope this information will be useful for your research of GABRP.
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References
- Zubor, P; Hatok, J; et al. Gene expression profiling of histologically normal breast tissue in females with human epidermal growth factor receptor 2-positive breast cancer. MOLECULAR MEDICINE REPORTS 11:1421-1427(2015).
- Sizemore, GM; Sizemore, ST; et al. GABA(A) Receptor Pi (GABRP) Stimulates Basal-like Breast Cancer Cell Migration through Activation of Extracellular-regulated Kinase 1/2 (ERK1/2). JOURNAL OF BIOLOGICAL CHEMISTRY 289:24102-24113(2014).
