Fert2
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Official Full Name
fer (fms/fps related) protein kinase, testis specific 2 -
Overview
FER is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. FER plays a role in regulating cytoskeletal rearrangements and inside out signalling that accompany receptor ligand, cell matrix and cell cell interactions. Genetic analysis using transgenic mouse models implicate FER in the regulation of inflammation and innate immunity. -
Synonyms
Fer;Flk;Flk_retired
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Fert2-310M | Recombinant Mouse Fert2, GST-tagged, Active | Sf9 Cells | Mouse | GST | 542-end a.a. |
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| FERT2-5819M | Recombinant Mouse FERT2 Protein | Mammalian Cells | Mouse | His |
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| FERT2-3211M | Recombinant Mouse FERT2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| FERT2-3211M-B | Recombinant Mouse FERT2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
Fert2 involved in several pathways and played different roles in them. We selected most pathways Fert2 participated on our site, such as Adherens junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with Fert2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adherens junction | CDC42L,PVRL1B,RAC3B,MET,ACTN3B,CSNK2A2,FER,CTNNB1,SNAI1,WASF1 |
Protein Function
Fert2 has several biochemical functions, for example, ATP binding,Rab GTPase binding,actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Fert2 itself. We selected most functions Fert2 had, and list some proteins which have the same functions with Fert2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein kinase binding | EEF1A2,CD36,ITGB2,GRB7,B4GALT1,TRIM22,CCNE1,RPTOR,MVP,CDK5 |
| protein kinase activity | AVP,RPS6KAL,STK3,MAP3K11,MAP2K1,DYRK1AA,WEE2,CASKB,LIMK1,CDC7 |
| actin binding | PLEC,ALKBH4,DNASE1,POF1B,MYH6,DIXDC1,SPIRE2,YWHAH,CFL1,SMYHC2 |
| protein phosphatase 1 binding | SH3RF2,PHACTR4B,PAWR,PHACTR3A,PPP1R9B,TCTEX1D4,STAU1,KCNQ1,SHOC2,PHACTR4 |
| cell adhesion molecule binding | NRXN3,PKP3,MSN,NCR3,ITGB7,ITGA4,PTPRD,JUP,PVRL3,NRXN1 |
| cytoskeletal protein binding | FABP3,PTPN4A,FLNC,ANXA2,ANXA2B,NCKIPSD,CAPN10,NEBL,CAPN2,EPB41B |
| gamma-catenin binding | APC,PTPRJ,PTPRK,LEF1,CDH2,CDH1,FER,PTBP3,DSG1,APC2 |
| ATP binding | ABCF1,ORC5,PHKG1B,DDX49,CAMKVB,PSMC5,QRSL1,DGKA,ACSM2B,LACE1 |
| protein tyrosine kinase activity | CLK3,MAP2K7,MUSK,CSF1RA,CSK,DYRK3,ABL2,FES,ERBB2,EPHB2 |
Interacting Protein
Fert2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Fert2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Fert2.
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