FYB
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Official Full Name
FYN binding protein -
Overview
The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene. -
Synonyms
FYB;FYN binding protein;FYN-binding protein;SLAP130;SLAP-130;p120/130;p120/p130;FYB-120/130;FYN-T-binding protein;SLP-76-associated phosphoprotein;adhesion and degranulation promoting adaptor protein;ADAP;B630013F22Rik
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FYB-3099C | Recombinant Chicken FYB | Mammalian Cell | Chicken | His |
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| FYB-6095HCL | Recombinant Human FYB 293 Cell Lysate | HEK293 | Human | Non |
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| Fyb-3117M | Recombinant Mouse Fyb Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| FYB-4583H | Recombinant Human FYB Protein, GST-tagged | Wheat Germ | Human | GST |
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| FYB-5282HF | Recombinant Full Length Human FYB Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 829 amino acids |
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Involved Pathway
FYB involved in several pathways and played different roles in them. We selected most pathways FYB participated on our site, such as Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FYB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Rap signaling pathway | MET,PIK3CG,RHOA,PDGFD,PARD6A,RASSF5,HGF,RAF1,FGF13,MAP2K3 |
Protein Function
FYB has several biochemical functions, for example, protein binding,protein complex binding,receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FYB itself. We selected most functions FYB had, and list some proteins which have the same functions with FYB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | NOC4L,GTF3C3,HADHB,SMURF2,NR5A2,RAB11FIP2,LIMK1,EIF4E,CSF1,PA2G4 |
| protein complex binding | PDCL,RNF40,FBN1,CASP8,NFKBIA,VAMP2,MTAP1B,GNB1,RBX1,TG |
| receptor binding | HLA-E,IZUMO1,NRG3,EPB49,F7,PGR,TNFSF9,GAS6,ECH1,CXCL12 |
Interacting Protein
FYB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FYB here. Most of them are supplied by our site. Hope this information will be useful for your research of FYB.
LCP2;FYN;SKAP1
Resources
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References
- Liu, XF; Li, LF; et al. Correlation between Duffy blood group phenotype and breast cancer incidence. BMC CANCER 12:-(2012).
- Wilkinson, K; Harris, S; et al. Molecular blood typing augments serologic testing and allows for enhanced matching of red blood cells for transfusion in patients with sickle cell disease. TRANSFUSION 52:381-388(2012).
