FRMPD2
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Official Full Name
FERM and PDZ domain containing 2 -
Overview
This gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene is full-length and is in the telomeric duplicated region. Two other more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full-length gene appears to function in the establishment and maintenance of cell polarization. The protein is recruited to cell-cell junctions in an E-cadherin-dependent manner, and is selectively localized at the basolateral membrane in polarized epithelial cells. Alternative splicing results in multiple transcript variants. -
Synonyms
FRMPD2;FERM and PDZ domain containing 2;PDZ domain containing 5C , PDZD5C, PDZK5C;FERM and PDZ domain-containing protein 2;MGC35285;FERM and PDZ domain containing protein 2;PDZ domain containing protein 4;PDZ domain containing protein 5C;PDZD5C;PDZK4;PDZK5C;PDZ domain containing 5C;PDZ domain-containing protein 4;PDZ domain-containing protein 5C
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FRMPD2-670HCL | Recombinant Human FRMPD2 cell lysate | Human | Non |
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| FRMPD2-4504H | Recombinant Human FRMPD2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| FRMPD2-5065HF | Recombinant Full Length Human FRMPD2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 261 amino acids |
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Involved Pathway
FRMPD2 involved in several pathways and played different roles in them. We selected most pathways FRMPD2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FRMPD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
FRMPD2 has several biochemical functions, for example, 1-phosphatidylinositol binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FRMPD2 itself. We selected most functions FRMPD2 had, and list some proteins which have the same functions with FRMPD2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CASQ2,TCEB3B,NDUFS2,CSRNP1,PVR,CEP350,CGGBP1,CCDC85B,DNAAF2,TFAM |
| 1-phosphatidylinositol binding | EPB41,PICALMA,SCARB1,ZFYVE1,CCDC167,PLEKHA3,WDFY3,PLEKHA2,SNX9,SCIN |
Interacting Protein
FRMPD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FRMPD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FRMPD2.
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