FRMD3
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Official Full Name
FERM domain containing 3 -
Overview
The protein encoded by this gene is a single pass membrane protein primarily found in ovaries. A similar protein in erythrocytes helps determine the shape of red blood cells, but the function of the encoded protein has not been determined. There is some evidence that this is a tumor suppressor gene, and there is also evidence linking defects in this gene to susceptibility to diabetic nephropathy in type 1 diabetes. Several transcript variants encoding different isoforms have been found for this gene. -
Synonyms
FRMD3;FERM domain containing 3;FERM domain-containing protein 3;EPB41L4O;MGC20553;4.1O;Band 4.1 like protein 4O;FERM domain containing protein 3;Ovary type protein 4.1;P410;protein 4.1O;band 4.1-like protein 4;band 4.1-like protein 4O;EPB41LO;RP11-439K3.2
Recombinant Proteins
- Mouse
- Human
- Mus musculus
- Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
- Pongo Abelii
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- E.coli expression system
- His
- Non
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FRMD3-6037M | Recombinant Mouse FRMD3 Protein | Mammalian Cell | Mouse | His |
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| FRMD3-668HCL | Recombinant Human FRMD3 cell lysate | Human | Non |
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| FRMD3-3358M | Recombinant Mouse FRMD3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| FRMD3-3358M-B | Recombinant Mouse FRMD3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| FRMD3-4499H | Recombinant Human FRMD3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| FRMD3-5152HF | Recombinant Full Length Human FRMD3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 581 amino acids |
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| RFL16173MF | Recombinant Full Length Mouse Ferm Domain-Containing Protein 3(Frmd3) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length (1-595) |
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| RFL3287XF | Recombinant Full Length Xenopus Tropicalis Ferm Domain-Containing Protein 3(Frmd3) Protein, His-Tagged | E.coli expression system | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | His | Full L. Full Length (1-600) |
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| RFL3676PF | Recombinant Full Length Pongo Abelii Ferm Domain-Containing Protein 3(Frmd3) Protein, His-Tagged | E.coli expression system | Pongo Abelii | His | Full L. Full Length (1-597) |
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| RFL9158HF | Recombinant Full Length Human Ferm Domain-Containing Protein 3(Frmd3) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-597) |
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Involved Pathway
FRMD3 involved in several pathways and played different roles in them. We selected most pathways FRMD3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FRMD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FRMD3 has several biochemical functions, for example, cytoskeletal protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FRMD3 itself. We selected most functions FRMD3 had, and list some proteins which have the same functions with FRMD3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytoskeletal protein binding | PACSIN2,NF2B,ALDOA,ACTN2,Fert2,NF2A,RPH3AL,TOR1AIP1,TNNT2A,MYLIP |
Interacting Protein
FRMD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FRMD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of FRMD3.
q8xaj5_eco57;ATP5D;ATP5O;OXA1L
FRMD3 Related Signal Pathway
Resources
Related Services
Related Products
References
- Alkayyali, S; Lyssenko, V; et al. Genetics of diabetes complications. MAMMALIAN GENOME 25:384-400(2014).
- Palmer, ND; Ng, MCY; et al. Evaluation of Candidate Nephropathy Susceptibility Genes in a Genome-Wide Association Study of African American Diabetic Kidney Disease. PLOS ONE 9:-(2014).
