FOXK1
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Official Full Name
forkhead box K1 -
Overview
Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli. -
Synonyms
FOXK1;forkhead box K1;FOXK1L;forkhead box protein K1;MNF;myocyte nuclear factor
Recombinant Proteins
- Zebrafish
- Human
- Mouse
- Mammalian Cell
- HEK293
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FOXK1-10272Z | Recombinant Zebrafish FOXK1 | Mammalian Cell | Zebrafish | His |
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| FOXK1-1479H | Recombinant Human FOXK1 | Mammalian Cell | Human | His |
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| FOXK1-5997M | Recombinant Mouse FOXK1 Protein | Mammalian Cell | Mouse | His |
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| FOXK1-2973H | Recombinant Human FOXK1 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| FOXK1-2973H-B | Recombinant Human FOXK1 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| FOXK1-3328M | Recombinant Mouse FOXK1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| FOXK1-3328M-B | Recombinant Mouse FOXK1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
FOXK1 involved in several pathways and played different roles in them. We selected most pathways FOXK1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FOXK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FOXK1 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding,RNA polymerase II transcription factor activity, sequence-specific DNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOXK1 itself. We selected most functions FOXK1 had, and list some proteins which have the same functions with FOXK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | KLF11,ZSCAN18,GCM1,FOXP1,ZMYM5,FOXE1,SP3,FOXC1A,TWIST1,PLAGX |
| RNA polymerase II regulatory region sequence-specific DNA binding | ZBTB12.2,KAT2B,ETV5,BHLHA15,EOMES,TAL1,HMX3,NME2,NR1I3,NKX2-1 |
| protein binding | AF251705,CHDH,PRKCQ,TYROBP,CXXC5,FAM125B,ERCC8,ERLIN1,MAVS,MED9 |
Interacting Protein
FOXK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOXK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FOXK1.
IRF2;AMOT;BAP1;FYCO1;comEA;Max;N;ssdna_dadts;SAP30;PDGFRB;HDAC1;RNPS1;P;Fam60a;Bap1
Resources
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References
- Okino, Y; Machida, Y; et al. BRCA1-associated Protein 1 (BAP1) Deubiquitinase Antagonizes the Ubiquitin-mediated Activation of FoxK2 Target Genes. JOURNAL OF BIOLOGICAL CHEMISTRY 290:1580-1591(2015).
- Bowman, CJ; Ayer, DE; et al. Foxk proteins repress the initiation of starvation-induced atrophy and autophagy programs. NATURE CELL BIOLOGY 16:1202-U173(2014).
