FOXD3
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Official Full Name
forkhead box D3 -
Overview
The FOXD3 Antibody recognizes human FOXD3 also known as Forkhead box protein D3 and HNF3/FH transcription factor genesis. FOXD3 belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain, predicted molecul -
Synonyms
FOXD3;forkhead box D3;forkhead box protein D3;Genesis;HFH2;HNF3/FH transcription factor genesis;AIS1;VAMAS2
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Zebrafish
- Rat
- Mammalian Cell
- E.coli
- HEK293
- His
- Arg
- His&Fc&Avi
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FOXD3-1062H | Recombinant Human FOXD3 | Mammalian Cell | Human | His |
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| FOXD3-144H | Recombinant Human FOXD3 protein, Arginine-tagged | E.coli | Human | Arg |
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| FOXD3-1741R | Recombinant Rhesus monkey FOXD3 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| FOXD3-6510C | Recombinant Chicken FOXD3 | Mammalian Cell | Chicken | His |
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| FOXD3-8881Z | Recombinant Zebrafish FOXD3 | Mammalian Cell | Zebrafish | His |
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| Foxd3-1515R | Recombinant Rat Foxd3 Protein, His-tagged | E.coli | Rat | His | Gln244-Phe479 |
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| FOXD3-1563R | Recombinant Rhesus Macaque FOXD3 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| FOXD3-1563R-B | Recombinant Rhesus Macaque FOXD3 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| FOXD3-2964H | Recombinant Human FOXD3 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| FOXD3-2964H-B | Recombinant Human FOXD3 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| FOXD3-301510H | Recombinant Human FOXD3 protein, GST-tagged | E.coli | Human | GST | Met1-Ser138 |
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Involved Pathway
FOXD3 involved in several pathways and played different roles in them. We selected most pathways FOXD3 participated on our site, such as Developmental Biology,Neural Crest Differentiation,POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation, which may be useful for your reference. Also, other proteins which involved in the same pathway with FOXD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neural Crest Differentiation | TFAP2B,LHX2,SOX5,OLIG2,SOX10,OLIG3,PHOX2B,OLIG1,MBP,CDH7 |
| POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation | TDGF1,NR6A1 |
| Wnt Signaling Pathway and Pluripotency | LRRK2,PPM1J,FBXW2,ZBTB33 |
| Developmental Biology | FRS2B,MED16,EPHA4A,SPTA1,RND1L,LAMTOR2,FGF18B,CLASP1,DCX,CCNC |
| Transcriptional regulation of pluripotent stem cells | HIF3A,POU5F3,TDGF1,PRDM14,LIN28A,NR6A1,SALL4,NR5A1 |
Protein Function
FOXD3 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding,protein binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOXD3 itself. We selected most functions FOXD3 had, and list some proteins which have the same functions with FOXD3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II regulatory region sequence-specific DNA binding | ARHGAP35,ZNF773,TFAP2C,ELF5,MSX1,CDX1A,RARG,ZBTB12.2,NME2,ZNF691 |
| transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding | GLIS1,SATB1,AEBP1,ISX,HIST2H3A,FOXO3,DMBX1,ARHGAP35,CGGBP1,MNT |
| transcription factor activity, sequence-specific DNA binding | ZHX3,NFIL3-4,GATA2B,LHX1,NR2F6A,PAX7,MECP2,PPARD,NEUROG1,FOXG1A |
| protein binding | TNFSF13B,TA,MLL1,CBX1,HRAS,DCTN4,MARCH10,MYO7A,FGFBP1,UBR2 |
Interacting Protein
FOXD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOXD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of FOXD3.
POU5F1
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References
- Guo, RJ; Wu, QH; et al. Description of the CD133(+) subpopulation of the human ovarian cancer cell line OVCAR3. ONCOLOGY REPORTS 25:141-146(2011).
- Gilbert, SF; Bender, G; et al. The contribution of neural crest cells to the nuchal bone and plastron of the turtle shell. INTEGRATIVE AND COMPARATIVE BIOLOGY 47:401-408(2007).
