FN3KRP
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Official Full Name
fructosamine 3 kinase related protein -
Overview
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine;residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which;catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a;highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes;may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript;variants. -
Synonyms
FN3KRP;fructosamine 3 kinase related protein;ketosamine-3-kinase;EC 2.7.1.-;FLJ12171;FN3K-related protein;FN3K-RP;FN3KL;Fn3krp fructosamine-3-kinase-related protein;FN3X;Fructosamine-3-kinase-related protein;MGC40640;RGD1304570;RP23-293H17.3
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- Myc&DDK
- GST
Involved Pathway
FN3KRP involved in several pathways and played different roles in them. We selected most pathways FN3KRP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FN3KRP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FN3KRP has several biochemical functions, for example, kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FN3KRP itself. We selected most functions FN3KRP had, and list some proteins which have the same functions with FN3KRP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| kinase activity | PHKG1B,ADKB,VPRBP,IGF1RA,FGFR1A,RPS6KA3A,HMGXB3,BAIAP2L1A,PAK2B,NTRK2B |
Interacting Protein
FN3KRP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FN3KRP here. Most of them are supplied by our site. Hope this information will be useful for your research of FN3KRP.
USP43
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References
- Chondrogianni, N; Petropoulos, I; et al. Protein damage, repair and proteolysis. MOLECULAR ASPECTS OF MEDICINE 35:1-71(2014).
- Tanhauserova, V; Kuricova, K; et al. Genetic variability in enzymes of metabolic pathways conferring protection against non-enzymatic glycation versus diabetes-related morbidity and mortality. CLINICAL CHEMISTRY AND LABORATORY MEDICINE 52:77-83(2014).
