FMN2
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Official Full Name
formin 2 -
Overview
Formin homology (FH) domain proteins (see FMN1; MIM 136535) play a role in cytoskeletal organization and/or establishment of cell polarity. -
Synonyms
FMN2;formin 2;formin-2;FMN 2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FMN2-12940H | Recombinant Human FMN2, GST-tagged | E.coli | Human | GST | C-term-214a.a. | |
| FMN2-3631H | Recombinant Human FMN2 protein, His-tagged | E.coli | Human | His | 1509-1722 aa | |
| FMN2-5934M | Recombinant Mouse FMN2 Protein | Mammalian Cell | Mouse | His |
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| FMN2-3286M | Recombinant Mouse FMN2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| FMN2-3286M-B | Recombinant Mouse FMN2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| FMN2-4387H | Recombinant Human FMN2 Protein, GST-tagged | Wheat Germ | Human | GST |
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Involved Pathway
FMN2 involved in several pathways and played different roles in them. We selected most pathways FMN2 participated on our site, such as Dorso-ventral axis formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with FMN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Dorso-ventral axis formation | ETV6,ETS1,ETS2,EGFRA,NOTCH1,PIWIL4,MAP2K1,GRB2B,GRB2,PIWIL1 |
Protein Function
FMN2 has several biochemical functions, for example, actin binding,molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by FMN2 itself. We selected most functions FMN2 had, and list some proteins which have the same functions with FMN2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | NF2,CAPZB,PHACTR1,EZRB,INF2,TLN2A,GC,MYHC4,FXYD5,CNN3B |
| molecular_function | KCNQ1DN,ZNF614,C11orf1,ASF1BB,RWDD4A,FAM105A,WFDC15A,FAM89A,TPRG,GM4179 |
Interacting Protein
FMN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FMN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FMN2.
Resources
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References
- Law, R; Dixon-Saazar, T; et al. Biallelic Truncating Mutations in FMN2, Encoding the Actin-Regulatory Protein Formin 2, Cause Nonsyndromic Autosomal-Recessive Intellectual Disability. AMERICAN JOURNAL OF HUMAN GENETICS 95:721-728(2014).
- Araujo, AN; Moraes, L; et al. Genome-Wide Copy Number Analysis in a Family With p.G533C RET Mutation and Medullary Thyroid Carcinoma Identified Regions Potentially Associated With a Higher Predisposition to Lymph Node Metastasis. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 99:E1104-E1112(2014).
