FLOT1
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Official Full Name
flotillin 1 -
Overview
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. FLOT1 encodes a caveolae-associated, integral membrane protein. The function of flotillin 1 has not been determined. [provided by RefSeq, Jul 2008] -
Synonyms
FLOT1;flotillin 1;flotillin-1;integral membrane component of caveolae
Recombinant Proteins
- Rhesus macaque
- Mouse
- Human
- Rat
- Mammalian Cell
- HEK293
- E.coli
- Mammalian cells
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- Flag
- Myc&DDK
- GST
Involved Pathway
FLOT1 involved in several pathways and played different roles in them. We selected most pathways FLOT1 participated on our site, such as Insulin Signaling,Insulin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FLOT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Insulin signaling pathway | HK3,RAF1A,PHKB,GSK3B,PTPRFB,EIF4EA,SH2B2,PRKAR2A,MAPK9,PRKAG2A |
| Insulin Signaling | EHD1,STXBP4,GRB10,MAPK6,STXBP3A,CAP1,STXBP1A,ARHGAP33,MAP3K2,GSK3AB |
Protein Function
FLOT1 has several biochemical functions, for example, protease binding,protein binding,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FLOT1 itself. We selected most functions FLOT1 had, and list some proteins which have the same functions with FLOT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | NDUFS3,SIK2,ALKBH8,RCHY1,ZBTB49,PEX12,KCTD9,INSIG2,STXBP1,IL13 |
| protein heterodimerization activity | GABPB2,TLR6,SYT14,SLC3A1,HIST1H2B5,ATP4A,PPP3CA,PAFAH1B3,FZD9,HIST1H4L |
| protease binding | CAST,SERPINB13,TIMP3,SERPINB3,INSL3,ECM1,TYSND1,ANXA2,STIM1,PEO1 |
Interacting Protein
FLOT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FLOT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FLOT1.
FLOT2;APP;ABCA1;env;ARG1;BBS7;BBS1
Resources
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References
- Karbanova, J; Laco, J; et al. Human PROMININ-1 (CD133) Is Detected in Both Neoplastic and Non-Neoplastic Salivary Gland Diseases and Released into Saliva in a Ubiquitinated Form. PLOS ONE 9:-(2014).
- Cordero, JG; Juarez, ML; et al. Caveolin-1 in Lipid Rafts Interacts with Dengue Virus NS3 during Polyprotein Processing and Replication in HMEC-1 Cells. PLOS ONE 9:-(2014).
