FLJ78302
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Official Full Name
CCR2 chemokine (C-C motif) receptor 2 -
Overview
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. -
Synonyms
CKR2;CCR2A;CCR2B;CD192;CKR2A;CKR2B;CMKBR2;MCP-1-R;CC-CKR-2;FLJ78302;MGC103828;MGC111760;MGC168006;C-C chemokine receptor type 2;CCR-2;C-C CKR-2;MCP-1 receptor;OTTHUMP00000209948;monocyte chemotactic protein 1 receptor;monocyte chemoattractant protein 1 receptor
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Involved Pathway
FLJ78302 involved in several pathways and played different roles in them. We selected most pathways FLJ78302 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FLJ78302 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
FLJ78302 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FLJ78302 itself. We selected most functions FLJ78302 had, and list some proteins which have the same functions with FLJ78302. You can find most of the proteins on our site.
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Interacting Protein
FLJ78302 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FLJ78302 here. Most of them are supplied by our site. Hope this information will be useful for your research of FLJ78302.
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