FGD3
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Official Full Name
FYVE, RhoGEF and PH domain containing 3 -
Overview
FYVE, RhoGEF and PH domain-containing protein 3 is a protein that in humans is encoded by the FGD3 gene. -
Synonyms
FGD3;FYVE, RhoGEF and PH domain containing 3;FGD1 family, member 3;FYVE, RhoGEF and PH domain-containing protein 3;FLJ00004;ZFYVE5;Faciogenital dysplasia 3;FYVE, RhoGEF and PH domain containing protein 3;Zinc finger FYVE domain containing protein 5;zinc finger FYVE domain-containing protein 5
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FGD3-12859H | Recombinant Human FGD3, GST-tagged | E.coli | Human | GST | C-term-156a.a. | |
| FGD3-27710TH | Recombinant Human FGD3, His-tagged | E.coli | Human | His | 518-725 a.a. |
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| FGD3-619HCL | Recombinant Human FGD3 cell lysate | Human | Non |
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| FGD3-4090H | Recombinant Human FGD3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| FGD3-4789HF | Recombinant Full Length Human FGD3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 725 amino acids |
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Involved Pathway
FGD3 involved in several pathways and played different roles in them. We selected most pathways FGD3 participated on our site, such as Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of Actin Cytoskeleton | F2R,VCLA,FGF6B,MYL2,PTK2AB,PXNA,ROCK2B,NCKAP1L,ITGB3,Fgf15 |
Protein Function
FGD3 has several biochemical functions, for example, Rho guanyl-nucleotide exchange factor activity,guanyl-nucleotide exchange factor activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGD3 itself. We selected most functions FGD3 had, and list some proteins which have the same functions with FGD3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| guanyl-nucleotide exchange factor activity | PTGIR,NET1,ARHGEF7B,RAPGEF1B,ANKRD27,RPGR,ARHGEF37,ARHGEF3L,PREX1,DOCK4 |
| Rho guanyl-nucleotide exchange factor activity | ARHGEF1,ARHGEF10,DOCK11,RASGRF2,ARHGEF3,MCF2L,PLEKHG6,FLJ20184,ARHGEF7B,ALS2CL |
| metal ion binding | PIR,SMAD9,ZNHIT3,ZFP710,ITPK1A,BMPR2,SOD3A,RPE65B,TDRD1,HMOX1A |
| small GTPase binding | ABCA1,FGD6,TSC2,RNF152,GDI2,FGD2,PEX5,PEX5L,FGD5,FGD4 |
Interacting Protein
FGD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGD3.
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References
- Yang, THO; Cheng, WY; et al. Breast Cancer Prognostic Biomarker Using Attractor Metagenes and the FGD3-SUSD3 Metagene. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 23:2850-2856(2014).
- Vu, MMK; Jameson, NE; et al. Convergent Evolution of Adenosine Aptamers Spanning Bacterial, Human, and Random Sequences Revealed by Structure-Based Bioinformatics and Genomic SELEX. CHEMISTRY & BIOLOGY 19:1247-1254(2012).
