FDX1
-
Official Full Name
ferredoxin 1 -
Synonyms
FDX1;ferredoxin 1;FDX;adrenodoxin, mitochondrial;adrenodoxin;ADX;ferredoxin-1;hepatoredoxin;adrenal ferredoxin;mitochondrial adrenodoxin;LOH11CR1D
Recombinant Proteins
- Human
- Rat
- Chicken
- Mouse
- E.coli
- Bovine
- E.coli
- Mammalian Cell
- E.Coli or Yeast
- HEK293
- Yeast
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- T7
- Non
- His&GST
- His&Fc&Avi
- Myc&DDK
- His&Myc
Involved Pathway
FDX1 involved in several pathways and played different roles in them. We selected most pathways FDX1 participated on our site, such as Biological oxidations,Cytochrome P450 - arranged by substrate type,Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR), which may be useful for your reference. Also, other proteins which involved in the same pathway with FDX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Diseases of metabolism | EPM2A,CCDC59,CYP11A1,FDX1L,GYG1,FDXR,AMN,GYG2,SFTPC,MMADHC |
| Endogenous sterols | CYP46A1,CYP11B1,CYP7A1,CYP8B2,FDXR,CYP27A1,CYP17A1,CYP51A1,CYP11B2,POMCB |
| Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR) | FDX1L,CYP11A1,FDXR |
| Biological oxidations | CYP2K22,DPEP2,CYP4T8,CYP2K6,ADH5,PAOX,UGT1B5,CYP26A1,ADH8A,CYP3C4 |
| Metabolic disorders of biological oxidation enzymes | FDX1L |
| Cytochrome P450 - arranged by substrate type | CYP2K6,CYP4F11,CYP2C19,CYP2W1,CYP2AD3,FAM84B,CYP2B6,CYP4F12,CYP2K19,CYP2A13 |
| Electron transport from NADPH to Ferredoxin | FDX1L,FDXR |
| Disease | MMAA,CUX1,SUPT5H,CDC37,STX1B,HMGA1,TCEA1,PPIA,CCNC,PRELP |
Protein Function
FDX1 has several biochemical functions, for example, 2 iron, 2 sulfur cluster binding,electron carrier activity,iron ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FDX1 itself. We selected most functions FDX1 had, and list some proteins which have the same functions with FDX1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| electron carrier activity | ACOXL,AKR7A2,AOX1,GSR,GRX2,DHDH,GLRX,UGDH,ALDH4A1,QDPR |
| iron ion binding | PLOD2,ETHE1,CYP19A1,CH25HL2,CYP2AA8,CYP2B6,SLC11A2,CYP3C1L2,CYP4T8,CYP21A2 |
| 2 iron, 2 sulfur cluster binding | UQCRFS1,ISCA2,FECH,SDHB,FXN,AOX1,FDX1B,CISD2,FDX1L,AIFM3 |
Interacting Protein
FDX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FDX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FDX1.
NR4A2;Prdx1;CAPZA2;HIF1A;CLPP;Cdc26;Lima1;GPATCH8
Resources
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References
- Millet, COM; Williams, CF; et al. Mitochondria-derived organelles in the diplomonad fish parasite Spironucleus vortens. EXPERIMENTAL PARASITOLOGY 135:262-273(2013).
- Rendon-Gandarilla, FJ; Ramon-Luing, LD; et al. The TvLEGU-1, a Legumain-Like Cysteine Proteinase, Plays a Key Role in Trichomonas vaginalis Cytoadherence. BIOMED RESEARCH INTERNATIONAL :-(2013).
