FCRL1
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Official Full Name
Fc receptor-like 1 -
Overview
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants. -
Synonyms
FCRL1;Fc receptor-like 1;Fc receptor-like protein 1;CD307a;FCRH1;IFGP1;IRTA5;RP11 367J7.7;Fc receptor homolog 1;Fc receptor like protein 1;FcR like protein 1;FCRH 1;FCRL 1;hIFGP 1;hIFGP1;IFGP 1;IFGP family protein 1;Immune receptor translocation associated protein 5;immunoglobulin superfamily Fc receptor, gp42;IRTA 5;fcR-like protein 1;immune receptor translocation-associated protein 5
Recombinant Proteins
- Human
- Rhesus macaque
- Mouse
- HEK293
- E.coli
- Wheat Germ
- Human Cell
- Mammalian cells
- In Vitro Cell Free System
- His
- His&GST
- Non
- Fc
- hIgG4
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FCRL1-3211H | Recombinant Human FCRL1 protein, His-tagged | HEK293 | Human | His | Met1-Asn303 | |
| FCRL1-027H | Recombinant Human FCRL1 protein, Gst-His-tagged | E.coli | Human | His&GST |
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| FCRL1-1709R | Recombinant Rhesus Monkey FCRL1 Protein | HEK293 | Rhesus macaque | Non | 17-300 a.a. |
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| FCRL1-1710R | Recombinant Rhesus Monkey FCRL1 Protein, hIgG1-tagged | HEK293 | Rhesus macaque | Fc | 17-300 a.a. |
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| FCRL1-1711R | Recombinant Rhesus Monkey FCRL1 Protein, hIgG4-tagged | HEK293 | Rhesus macaque | hIgG4 | 17-300 a.a. |
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| FCRL1-4005H | Recombinant Human FCRL1 Protein | Wheat Germ | Human | Non |
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| FCRL1-4006H | Recombinant Human FCRL1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| Fcrl1-8689M | Recombinant Mouse FCRL1 protein(Met1-Thr204), His-tagged | HEK293 | Mouse | His | 1-204 a.a. |
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| FCRL1-1379MCL | Recombinant Mouse FCRL1 cell lysate | Human Cell | Mouse | Non |
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| FCRL1-2227HCL | Recombinant Human FCRL1 cell lysate | Human Cell | Human | Non |
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| FCRL1-2803H | Recombinant Human FCRL1 Protein (Ala17-Asn303), C-His tagged | Mammalian cells | Human | His | Ala17-Asn303 |
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| FCRL1-3990H | Recombinant Human FCRL1 Protein (Met1-Ser307), C-His tagged | Mammalian cells | Human | His | Met1-Ser307 |
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| FCRL1-4767HF | Recombinant Full Length Human FCRL1 Protein | In Vitro Cell Free System | Human | Full L. 458 amino acids |
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| FCRL1-4768HF | Recombinant Full Length Human FCRL1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 429 amino acids |
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| Fcrl1-5760M | Recombinant Mouse Fcrl1 Protein (Ala17-Ser219), C-His tagged | Mammalian cells | Mouse | His | Ala17-Ser219 |
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Involved Pathway
FCRL1 involved in several pathways and played different roles in them. We selected most pathways FCRL1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FCRL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
FCRL1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FCRL1 itself. We selected most functions FCRL1 had, and list some proteins which have the same functions with FCRL1. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
FCRL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCRL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FCRL1.
Resources
Research Area
Fc ReceptorsITIM/ITAM Immunoreceptors and Related Molecules
B Cell Receptor-Associated Proteins
Related Services
Related Products
References
- Shabani, M; Bayat, AA; et al. Ligation of human Fc receptor like-2 by monoclonal antibodies down-regulates B-cell receptor-mediated signalling. IMMUNOLOGY 143:341-353(2014).
- Shabani, M; Hemmati, A; et al. Cloning, Expression and Characterization of Recombinant Human Fc Receptor Like 1, 2 and 4 Molecules. IRANIAN JOURNAL OF BIOTECHNOLOGY 11:182-192(2013).
