FCGR2C

  • Official Full Name

    FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) [ Homo sapiens ]

  • Overview

    This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants.

  • Synonyms

    Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene);15626;low affinity immunoglobulin gamma Fc region receptor II-c;fc-gamma-RIIc;IgG Fc receptor II-c;Fc gamma receptor IIC;immunoglobulin G Fc receptor II-c;CD32;FCG2;CD32C;CDW32;IGFR2;FCRIIC
Cat.# Product name Source (Host) Species Tag Protein Length Price
FCGR2C-12821H Recombinant Human FCGR2C, GST-tagged E.coli Human GST C-term-70a.a.
RFL32664HF Recombinant Full Length Human Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-C(Fcgr2C) Protein, His-Tagged E.coli expression system Human His Full L. Full Length of Mature Protein (43-323)

    Involved Pathway

    FCGR2C involved in several pathways and played different roles in them. We selected most pathways FCGR2C participated on our site, such as Phagosome,Osteoclast differentiation,Leishmaniasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with FCGR2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Osteoclast differentiation LILRB1,NCF2,CYBB,PPARG,SIRPG,SFPI1,LILRA3,CYLD,CYBA,TNFRSF1A
    Phagosome FCGR3A,NCF2,SEC22BA,THBS3,SEC22BB,CALRL2,ITGA2,CLEC7A,MHC2DEB,SEC61G
    Tuberculosis RFXAP,MAPK13,IL6,CD209,TGFB1,IFNA4,IFNA14,IL10RB,PPP3R1,ATP6V0A1
    Leishmaniasis HLA-DQB1,STAT1,MAP3K7,FCGR4,MAPK12,ITGA4,HLA-DRA,HLA-DRB5,MAPK11,RELA
    Staphylococcus aureus infection HLA-DRA,HLA-DQB1,C1S,HLA-DMB,C1QC,DSG1A,HLA-DQA2,C3,C2,FCGR1

    Protein Function

    FCGR2C has several biochemical functions, for example, IgG binding,protein binding,transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FCGR2C itself. We selected most functions FCGR2C had, and list some proteins which have the same functions with FCGR2C. You can find most of the proteins on our site.

    Function Related Protein
    IgG binding FCGR1A,CD247L,FCGR3A,UMOD,cgr2b,FCGRT,FCGR3B,FCGR2B,FCER1G,PIP
    protein binding FERD3L,COX5B,ZNF433,NRAP,RBM39,CATSPERG2,MED17,H3F3A,ATXN10,ACTR10
    transmembrane signaling receptor activity CD3G,CLEC4A,GP6,CD27,NFAM1,OR4C12,LYVE1,NPR2,MRC1,KLRD1

    Interacting Protein

    FCGR2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCGR2C here. Most of them are supplied by our site. Hope this information will be useful for your research of FCGR2C.

    Resources

    Research Area

    Granulocyte Markers
    CD Antigen (Granulocyte Markers)
    Thymus-Independent B Cell Activation
    Dendritic Cell Pathogen Recognition/Uptake
    MDSC Phenotyping - Positive Markers

    References

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