FBXO7
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Official Full Name
F-box protein 7 -
Overview
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined. -
Synonyms
FBXO7;F-box protein 7;F box only protein 7;F-box only protein 7;Fbx;FBX7;PARK15;PKPS;FBX07;DKFZp686B08113
Recombinant Proteins
- Rhesus macaque
- Chicken
- Rat
- Zebrafish
- Human
- Mouse
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
Involved Pathway
FBXO7 involved in several pathways and played different roles in them. We selected most pathways FBXO7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FBXO7 has several biochemical functions, for example, protein binding,protein kinase binding,ubiquitin-protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO7 itself. We selected most functions FBXO7 had, and list some proteins which have the same functions with FBXO7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | S100B,CHMP1B,TRAPPC5,ELP3,STXBP3A,HHLA3,FAIM,GATA3,TK1,EDNRB |
| ubiquitin-protein transferase activity | RNF151,RNF213,BTR22,MDM2,PDZRN3B,ITCH,UHRF1,UBR4,RC3H2,ITCHA |
| protein kinase binding | RAB11FIP2,CAMK2N1A,PTPRK,ADIPOR1,HIF1A,NIPAL1,IKBKB,AKAP5,ATP1A1,NPR1 |
Interacting Protein
FBXO7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO7 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO7.
SKP1;PSMF1;PARK2
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