FBXO40
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Official Full Name
F-box protein 40 -
Overview
Members of the F-box protein family, such as FBXO40, are characterized by an approximately 40-amino acid F-box motif.;SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as;protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination;targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)). -
Synonyms
FBXO40;F-box protein 40;F-box only protein 40;Fbx40;KIAA1195;F box only protein 40;Muscle disease related protein;muscle disease-related protein
Recombinant Proteins
- Human
- Mouse
- Wheat Germ
- Mammalian Cell
- Insect Cell
- HEK293T
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Strep
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FBXO40-3946H | Recombinant Human FBXO40 Protein, GST-tagged | Wheat Germ | Human | GST |
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| FBXO40-5751M | Recombinant Mouse FBXO40 Protein | Mammalian Cell | Mouse | His |
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| FBXO40-607HCL | Recombinant Human FBXO40 cell lysate | Human | Non |
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| FBXO40-0870H | Recombinant Human FBXO40 Protein (G2-S709), Tag Free | Insect Cell | Human | Non | G2-S709 |
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| FBXO40-0871H | Recombinant Human FBXO40 Protein (G2-S709), His/Strep tagged | Insect Cell | Human | His&Strep | G2-S709 |
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| FBXO40-1046H | Recombinant Human FBXO40 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Fbxo40-2970M | Recombinant Mouse Fbxo40 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| FBXO40-3167M | Recombinant Mouse FBXO40 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| FBXO40-3167M-B | Recombinant Mouse FBXO40 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| FBXO40-4677HF | Recombinant Full Length Human FBXO40 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 709 amino acids |
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Involved Pathway
FBXO40 involved in several pathways and played different roles in them. We selected most pathways FBXO40 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO40 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
FBXO40 has several biochemical functions, for example, molecular_function,ubiquitin protein ligase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO40 itself. We selected most functions FBXO40 had, and list some proteins which have the same functions with FBXO40. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | ZFYVE20,PDZRN4,MAN2A2,ADAM18,RNF217,RARGB,AJUBA,NRD1B,BIRC5,DRL |
| molecular_function | ARRDC2,FHAD1,PPP1R27B,CCDC106B,COL24A1,PBLD2,SMC5,TPRN,IBSP,TMEM126B |
| ubiquitin protein ligase activity | RNF14,MED17,UBE2C,PELI1,CDK8,MED24,PDZRN4,RNF144AA,CDC34B,ANKIB1 |
Interacting Protein
FBXO40 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO40 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO40.
HSP90AB1
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References
- Palus, S; von Haehling, S; et al. Muscle wasting: an overview of recent developments in basic research. JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE 5:193-198(2014).
- Kirk-Ballard, H; Kilroy, G; et al. An ethanolic extract of Artemisia dracunculus L. regulates gene expression of ubiquitin-proteasome system enzymes in skeletal muscle: Potential role in the treatment of sarcopenic obesity. NUTRITION 30:S21-S25(2014).
