FBXO34

  • Official Full Name

    F-box protein 34
  • Overview

    Members of the F-box protein family, such as FBXO34, are characterized by an approximately 40-amino acid F-box motif.;SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as;protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination;targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)).
  • Synonyms

    FBXO34;F-box protein 34;F box only protein 34;F-box only protein 34;Fbx34;FLJ20725;CGI 301;F box protein 34;FBX34_HUMAN;protein CGI-301;CGI-301

Recombinant Proteins

  • Rhesus macaque
  • Chicken
  • Human
  • Mouse
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • His
  • GST
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
FBXO34-1664R Recombinant Rhesus monkey FBXO34 Protein, His-tagged Mammalian Cell Rhesus macaque His
FBXO34-2876C Recombinant Chicken FBXO34 Mammalian Cell Chicken His
FBXO34-3939H Recombinant Human FBXO34 Protein, GST-tagged Wheat Germ Human GST
FBXO34-5746M Recombinant Mouse FBXO34 Protein Mammalian Cell Mouse His
FBXO34-604HCL Recombinant Human FBXO34 cell lysate Human Non
FBXO34-1488R Recombinant Rhesus Macaque FBXO34 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
FBXO34-1488R-B Recombinant Rhesus Macaque FBXO34 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
FBXO34-3162M Recombinant Mouse FBXO34 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
FBXO34-3162M-B Recombinant Mouse FBXO34 Protein Pre-coupled Magnetic Beads HEK293 Mouse
FBXO34-4672HF Recombinant Full Length Human FBXO34 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 711 amino acids

    Involved Pathway

    FBXO34 involved in several pathways and played different roles in them. We selected most pathways FBXO34 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO34 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    FBXO34 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO34 itself. We selected most functions FBXO34 had, and list some proteins which have the same functions with FBXO34. You can find most of the proteins on our site.

    Function Related Protein
    protein binding ZBED1,GCH1,CCDC153,MCCC1,FZD5,HIST1H3D,WWC1,ARAP3,TOB1A,NUP107

    Interacting Protein

    FBXO34 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO34 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO34.

    MTUS2;KRT40;MDFI;HSP90AB1;SKP1

    Resources

    References

    • Xiao, J; Zhang, T; et al. FBXL20-mediated Vps34 ubiquitination as a p53 controlled checkpoint in regulating autophagy and receptor degradation. GENES & DEVELOPMENT 29:184-196(2015).
    • Ikram, S; Durandet, M; et al. Functional redundancy and/or ongoing pseudogenization among F-box protein genes expressed in Arabidopsis male gametophyte. PLANT REPRODUCTION 27:95-107(2014).

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