FBXO31
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Official Full Name
F-box protein 31 -
Overview
Members of the F-box protein family, such as FBXO31, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)). -
Synonyms
FBXO31;F-box protein 31;F box only protein 31;F-box only protein 31;FBX14;Fbx31;FBXO14;MGC15419;DKFZp434B027;DKFZp434J1815;FBX31_HUMAN;FLJ22477;MGC9527;pp2386;Putative breast cancer tumor suppressor;SCF ubiquitin ligase specificity factor;putative breast cancer tumor-suppressor
Recombinant Proteins
- Rhesus macaque
- Rat
- Human
- Mouse
- Mammalian Cell
- E.coli
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
FBXO31 involved in several pathways and played different roles in them. We selected most pathways FBXO31 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO31 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FBXO31 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO31 itself. We selected most functions FBXO31 had, and list some proteins which have the same functions with FBXO31. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
FBXO31 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO31 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO31.
SKP1;FAM58A;PDLIM1;MYH6;PRPS1;STX3;CUL1;EFR3A;QSER1;C18orf21;EDRF1;ZCCHC9;Kctd5;MRPS27;DNAJC19;CEP170P1;Skp1
Resources
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References
- Zhang, XC; Kong, Y; et al. F-box protein FBXO31 is down-regulated in gastric cancer and negatively regulated by miR-17 and miR-20a. ONCOTARGET 5:6178-6190(2014).
- Seeley, AH; Durham, MA; et al. Macrocerebellum, Epilepsy, Intellectual Disability, and Gut Malrotation in a Child With a 16q24.1-q24.2 Contiguous Gene Deletion. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164A:2062-2068(2014).
