FBXO30
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Official Full Name
F-box protein 30 -
Overview
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it is upregulated in nasopharyngeal carcinoma. -
Synonyms
FBXO30;F-box protein 30;F box only protein, helicase, 18;F-box only protein 30;Fbx30;MGC21674;F box domain protein;F box only protein 30;F-box domain protein;F-box only protein, helicase, 18
Recombinant Proteins
- Rhesus macaque
- Rat
- Human
- Mouse
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
Involved Pathway
FBXO30 involved in several pathways and played different roles in them. We selected most pathways FBXO30 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO30 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FBXO30 has several biochemical functions, for example, ubiquitin protein ligase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO30 itself. We selected most functions FBXO30 had, and list some proteins which have the same functions with FBXO30. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin protein ligase activity | RNF126,PJA1,DZIP3,CMTM2A,TRAF6,FBXL22,RNF34,TRAIP,ASB4,G2E3 |
| zinc ion binding | ZNRD1,PHEX,MYT1,MMP12,RASGRP1,GATA2A,NR1D2B,CAR13,USP3,LIMK1 |
Interacting Protein
FBXO30 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO30 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO30.
Dynll1;APC;Trappc11;MYO1C;DYNLL1;SKP1;QSOX2;Skp1
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