FBXO21
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Official Full Name
F-box protein 21 -
Overview
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants. -
Synonyms
FBXO21;F-box protein 21;F box only protein 21;F-box only protein 21;FBX21;KIAA0875;F box protein 21;FBX21_HUMAN
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FBXO21-3920H | Recombinant Human FBXO21 Protein, GST-tagged | Wheat Germ | Human | GST |
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| FBXO21-5735M | Recombinant Mouse FBXO21 Protein | Mammalian Cell | Mouse | His |
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| FBXO21-6305HCL | Recombinant Human FBXO21 293 Cell Lysate | HEK293 | Human | Non |
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| FBXO21-3153M | Recombinant Mouse FBXO21 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| FBXO21-3153M-B | Recombinant Mouse FBXO21 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| FBXO21-5025HF | Recombinant Full Length Human FBXO21 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 621 amino acids |
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Involved Pathway
FBXO21 involved in several pathways and played different roles in them. We selected most pathways FBXO21 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
FBXO21 has several biochemical functions, for example, DNA binding,ubiquitin-protein transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO21 itself. We selected most functions FBXO21 had, and list some proteins which have the same functions with FBXO21. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin-protein transferase activity | FBXO2,MALT1,FBXW11,SIAH1,BTR22,G2E3,RNF220,TRIM71,CDC23,SKP1 |
| DNA binding | OTPA,PURG,DDX41,NFYB,ZBTB5,SIX6,HER12,H2AFJ,TA,ZNF41 |
Interacting Protein
FBXO21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO21 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO21.
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