FBXO15
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Official Full Name
F-box protein 15 -
Overview
Members of the F-box protein family, such as FBXO15, are characterized by an approximately 40-amino acid F-box motif.;SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as;protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination;targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)). -
Synonyms
FBXO15;F-box protein 15;F box only protein 15;F-box only protein 15;FBX15;MGC39671;F box protein 15
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FBXO15-3915H | Recombinant Human FBXO15 Protein, GST-tagged | Wheat Germ | Human | GST |
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| FBXO15-5020HF | Recombinant Full Length Human FBXO15 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 434 amino acids |
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Involved Pathway
FBXO15 involved in several pathways and played different roles in them. We selected most pathways FBXO15 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXO15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
FBXO15 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FBXO15 itself. We selected most functions FBXO15 had, and list some proteins which have the same functions with FBXO15. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
FBXO15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXO15 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXO15.
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References
- Chen, BB; Coon, TA; et al. E3 Ligase Subunit Fbxo15 and PINK1 Kinase Regulate Cardiolipin Synthase 1 Stability and Mitochondrial Function in Pneumonia. CELL REPORTS 7:476-487(2014).
- Katayama, K; Noguchi, K; et al. FBXO15 regulates P-glycoprotein/ABCB1 expression through the ubiquitinproteasome pathway in cancer cells. CANCER SCIENCE 104:694-702(2013).
