FBXL12
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Official Full Name
F-box and leucine-rich repeat protein 12 -
Overview
Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif.;SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as;protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination;targets through other protein interaction domains (Jin et al., 2004 (PubMed 15520277)). -
Synonyms
FBXL12;F-box and leucine-rich repeat protein 12;F-box/LRR-repeat protein 12;Fbl12;FLJ20188;F box and leucine rich repeat protein 12;F box protein FBL12;F box/LRR repeat protein 12;FBXL 12;F-box protein FBL12
Recombinant Proteins
- Human
- Mouse
- Chicken
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FBXL12-2965H | Recombinant Human FBXL12 protein, His-tagged | E.coli | Human | His | 170-326 aa | |
| FBXL12-3887H | Recombinant Human FBXL12 Protein, GST-tagged | Wheat Germ | Human | GST |
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| FBXL12-5711M | Recombinant Mouse FBXL12 Protein | Mammalian Cell | Mouse | His |
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| FBXL12-7033C | Recombinant Chicken FBXL12 | Mammalian Cell | Chicken | His |
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| FBXL12-6314HCL | Recombinant Human FBXL12 293 Cell Lysate | HEK293 | Human | Non |
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| Fbxl12-2960M | Recombinant Mouse Fbxl12 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| FBXL12-3139M | Recombinant Mouse FBXL12 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| FBXL12-3139M-B | Recombinant Mouse FBXL12 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| FBXL12-4921HF | Recombinant Full Length Human FBXL12 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 326 amino acids |
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| FBXL12-577H | Recombinant Human FBXL12 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
FBXL12 involved in several pathways and played different roles in them. We selected most pathways FBXL12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FBXL12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FBXL12 has several biochemical functions, for example, protein binding,contributes_to ubiquitin protein ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FBXL12 itself. We selected most functions FBXL12 had, and list some proteins which have the same functions with FBXL12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to ubiquitin protein ligase activity | CUL4B,FBXL3A,FBXL14,FBXL6,FBXL5,CUL4A,FBXL14A,UBXN6,CUL2,FBXL15 |
| protein binding | PTTG1IP,PYYA,DIABLO,FLT1,SENP1,PPIA,SIGIRR,PIM1,MCCC2,ENTPD3 |
Interacting Protein
FBXL12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBXL12 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBXL12.
DOCK8;LNX1;RNF32;CDKN1C;HSP90AB1;PSEN2;FXYD3;CDC37;MAST1;RBX1
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