FARP2
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Official Full Name
FERM, RhoGEF and pleckstrin domain protein 2 -
Overview
FERM, RhoGEF and pleckstrin domain-containing protein 2 is a protein that in humans is encoded by the FARP2 gene. -
Synonyms
FARP2;FERM, RhoGEF and pleckstrin domain protein 2;FERM, RhoGEF and pleckstrin domain-containing protein 2;FIR;FRG;KIAA0793;PLEKHC3;FARP 2;FERM;FGD1 related Cdc42 GEF;RhoGEF and pleckstrin domain protein 2;OTTHUMP00000200233;FGD1-related Cdc42-GEF;FERM domain including RhoGEF;PH domain-containing family C member 3;pleckstrin homology domain-containing family C member 3
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| FARP2-3842H | Recombinant Human FARP2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| FARP2-5681M | Recombinant Mouse FARP2 Protein | Mammalian Cell | Mouse | His |
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| FARP2-3118M | Recombinant Mouse FARP2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| FARP2-3118M-B | Recombinant Mouse FARP2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| FARP2-4713HF | Recombinant Full Length Human FARP2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 647 amino acids |
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Involved Pathway
FARP2 involved in several pathways and played different roles in them. We selected most pathways FARP2 participated on our site, such as Rap signaling pathway,Adherens junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with FARP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Rap signaling pathway | ITGB1,ACTG1,FGF19,GNAQ,NGFR,CALM4,RAC1,PLCG1,PARD3,PIK3CD |
| Adherens junction | CSNK2A1,INSRA,INSRB,TCF7L1A,SSX2IP,PTPN6,WASF3,CSNK2B,RAC3A,NLK |
Protein Function
FARP2 has several biochemical functions, for example, Rac guanyl-nucleotide exchange factor activity,Rho guanyl-nucleotide exchange factor activity,cytoskeletal protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FARP2 itself. We selected most functions FARP2 had, and list some proteins which have the same functions with FARP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| Rho guanyl-nucleotide exchange factor activity | ARHGEF16,SOS1,QUO,FGD4,KALRNB,ARHGEF40,C3A.1,ARHGEF39,C9orf100,BCR |
| guanyl-nucleotide exchange factor activity | ARHGEF19,ARHGEF37,EIF2B5,ARHGEF7B,KNDC1,RASGRP2,TBXAS1,ARHGEF7A,ARHGEF17,ARFGEF2 |
| Rac guanyl-nucleotide exchange factor activity | ALS2,DOCK2,ARHGEF2,VAV1,VAV3,FARP1,SPATA13,PREX2,ARHGEF4 |
| cytoskeletal protein binding | ACTN2,PKD2L1,PTPN4A,ALDOA,NF2A,PTPN3,PACSIN1,EPB41L3A,MYPN,MSNA |
Interacting Protein
FARP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FARP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FARP2.
Hmga2;Ywhah
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References
- DiTommaso, T; Jones, LK; et al. Identification of Genes Important for Cutaneous Function Revealed by a Large Scale Reverse Genetic Screen in the Mouse. PLOS GENETICS 10:-(2014).
- Mlechkovich, G; Peng, SS; et al. Distinct Cytoplasmic Domains in Plexin-A4 Mediate Diverse Responses to Semaphorin 3A in Developing Mammalian Neurons. SCIENCE SIGNALING 7:-(2014).
