FAIM3
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Official Full Name
Fas apoptotic inhibitory molecule 3 -
Overview
Apoptosis is an important process in maintaining normal tissue homeostasis and function. One of the major signals that regulate this process is mediated by the activation of the Fas receptor by its ligand. This leads to the formation of a Fas associated death domain (FADD), containing death inducing signalling complex, and the activation of caspase-8, which in turn activates downstream effector caspases, such as caspase-3 and -7 (Curting and Cotter, 2003). -
Synonyms
Fas apoptotic inhibitory molecule 3;FAIM3;FCMR;TOSO;Fc mu receptor;IgM Fc receptor;OTTHUMP00000034619;OTTHUMP00000228559;immunoglobulin mu Fc receptor;regulator of Fas-induced apoptosis Toso
Recombinant Proteins
- Rhesus macaque
- Rat
- Human
- Mouse
- Mammalian Cell
- Human Cell
- HEK293
- E.coli
- His
- Fc
- Non
- His&Fc&Avi
- His&SUMO
Involved Pathway
FAIM3 involved in several pathways and played different roles in them. We selected most pathways FAIM3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FAIM3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FAIM3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FAIM3 itself. We selected most functions FAIM3 had, and list some proteins which have the same functions with FAIM3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
FAIM3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAIM3 here. Most of them are supplied by our site. Hope this information will be useful for your research of FAIM3.
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Resources
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References
- Ding, ZJ; Bergman, A; et al. Complement-Activating IgM Enhances the Humoral but Not the T Cell Immune Response in Mice. PLOS ONE 8:-(2013).
- Kubagawa, H; Kubagawa, Y; et al. The Old but New IgM Fc Receptor (Fc mu R). FC RECEPTORS 382:3-28(2014).
