F2RL3
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Official Full Name
coagulation factor II (thrombin) receptor-like 3 -
Overview
Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin. -
Synonyms
F2RL3;coagulation factor II (thrombin) receptor-like 3;proteinase-activated receptor 4;PAR4;proteinase activated receptor 4;PAR-4;thrombin receptor-like 3;protease-activated receptor-4;proteinase-activated receptor-4;coagulation factor II recepto
Recombinant Proteins
- Human
- Rat
- Mouse
- Mus musculus
- E.coli
- HEK293
- Mammalian Cell
- Wheat Germ
- HEK293T
- E.coli expression system
- His
- Non
- GST
- His&Fc&Avi
- Myc&DDK
Involved Pathway
F2RL3 involved in several pathways and played different roles in them. We selected most pathways F2RL3 participated on our site, such as Rap signaling pathway,Neuroactive ligand-receptor interaction,Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with F2RL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Platelet activation | ITPR3,TLN1,ARHGEF12,PRKACB,Adcy4,PLCB3,ITGA2,ITGB1,TBXA2R,GNAI3 |
| Rap signaling pathway | IGF1,BRAF,CDH1,CDC42,NRAS,FGF10,MAPK3,PFN3,RAF1,PFN2 |
| Neuroactive ligand-receptor interaction | MAS1,NPFFR1L3,DRD2L,TAAR10B,THRAA,GABRR2,CHRNA4B,GABRR1,P2RY11,TSHB |
| Pathways in cancer | EPAS1,LAMA5,HGF,CBLC,ROCK2,FGF13,NFKBIA,PIK3CB,MSH3,SMO |
Protein Function
F2RL3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by F2RL3 itself. We selected most functions F2RL3 had, and list some proteins which have the same functions with F2RL3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
F2RL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with F2RL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of F2RL3.
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