Ecel1
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Official Full Name
ECEL1 endothelin converting enzyme-like 1 [ Homo sapiens ] -
Overview
This gene encodes a member of the M13 family of endopeptidases. In general, M13 family members are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. This gene is expressed specifically in the central nervous system and its protein localizes predominately to the endoplasmic reticulum or, in trace amounts, to the cell surface. Disruption of this gene in mouse embryonic stem cells results in neonatal lethality due to respiratory failure shortly after birth. Based on the specific expression of this gene and the phenotype of the gene deficiency in mouse embryos, it is suggested that this protein plays a critical role in neural regulation of the respiratory system. This gene has multiple pseudogenes. -
Synonyms
endothelin converting enzyme-like 1;3147;Ensembl:ENSG00000171551;endothelin-converting enzyme-like 1;X converting enzyme;damage induced neuronal endopeptidase;XCE;DINE;ECEX
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
- His&Myc
Involved Pathway
Ecel1 involved in several pathways and played different roles in them. We selected most pathways Ecel1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Ecel1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
Ecel1 has several biochemical functions, for example, metal ion binding,metalloendopeptidase activity,metallopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Ecel1 itself. We selected most functions Ecel1 had, and list some proteins which have the same functions with Ecel1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metallopeptidase activity | PAPLNB,ADAM1B,DPP3,DNPEP,CNDP1,STAMBPL1,MMP9,ADAM8A,ANPEP,ACY1 |
| metal ion binding | ZFP511,ZHX1,ZCCHC16,CHSY3,ZNF689,ZNF395A,FAM164C,RNF144AA,AGAP2,CYB5D1 |
| metalloendopeptidase activity | MEP1A.1,ADAMTS7,TLL2,ADAMTS9,ADAM23,KEL,PAPLN,UQCRC1,MMP1,PAPPA |
Interacting Protein
Ecel1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ecel1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ecel1.
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