EVX2

  • Official Full Name

    eve, even-skipped homeobox homolog 2
  • Overview

    This gene is located at the 5 end of the HOXD gene cluster on chromosome 2. The encoded protein is a homeobox transcription factor that is related to the protein encoded by the Drosophila even-skipped (eve) gene, a member of the pair-rule class of segmentation genes. A 117 kb microdeletion at the 5 end of the HOXD gene cluster, which includes this gene and the HOXD9-HOXD13 genes, causes synpolydactyly, a dominantly inherited disease resulting in limb malformation.
  • Synonyms

    EVX2;eve, even-skipped homeobox homolog 2 (Drosophila);eve, even skipped homeobox homolog 2 (Drosophila);eve, even-skipped homeobox homolog 2;Even-skipped homeo box-2;eve, even-skipped homeo box homolog 2 (Drosophila);even-skipped homeo box 2 (homol
Cat.# Product name Source (Host) Species Tag Protein Length Price
EVX2-8831Z Recombinant Zebrafish EVX2 Mammalian Cell Zebrafish His

    Involved Pathway

    EVX2 involved in several pathways and played different roles in them. We selected most pathways EVX2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with EVX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    EVX2 has several biochemical functions, for example, DNA binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EVX2 itself. We selected most functions EVX2 had, and list some proteins which have the same functions with EVX2. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding ZFP143,IRX4B,ZNF266,ZSCAN5A,ZNF766,ZNF670,SP6,AHR1A,CHD4,FOXO3B
    sequence-specific DNA binding LEF1,POU1F1,FOXI1,IRX4,LMX1A,ZNF75D,FOXP4,SPI1B,MAFBA,PKNOX1.1

    Interacting Protein

    EVX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EVX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EVX2.

    Resources

    References

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