EVC

  • Official Full Name

    Ellis van Creveld syndrome
  • Overview

    This gene encodes a protein containing a leucine zipper and a transmembrane domain. This gene has been implicated in both Ellis-van Creveld syndrome (EvC) and Weyers acrodental dysostosis.
  • Synonyms

    EVC;Ellis van Creveld syndrome;ellis-van Creveld syndrome protein;DWF 1;DWF1;Ellis van Creveld syndrome protein;EVC1;EVCL;MGC105107;DWF-1
Cat.# Product name Source (Host) Species Tag Protein Length Price
EVC-1243C Recombinant Chicken EVC Mammalian Cell Chicken His
EVC-3543H Recombinant Human EVC Protein, GST-tagged Wheat Germ Human GST
EVC-577HCL Recombinant Human EVC cell lysate Human Non
EVC-2297H Recombinant Human EVC Protein, MYC/DDK-tagged HEK293 Human Myc&DDK
Evc-2883M Recombinant Mouse Evc Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
EVC-4374HF Recombinant Full Length Human EVC Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 535 amino acids

    Involved Pathway

    EVC involved in several pathways and played different roles in them. We selected most pathways EVC participated on our site, such as Activation of SMO,Hedgehog on state,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with EVC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Signaling by Hedgehog CDON,GAS8,INTU,HHAT,MKS1,GPR161,TTC21B,IQCE,IFT172,BOC
    Signal Transduction SPOP,RLN3A,NRP2,SOX13,OBSCN,CLIP3,ABI1B,IFT172,STARD13,RAMP1
    Hedgehog on state GPR161,MKS1,IQCE,CDON,SPOPL,IFT172,BOC,GAS8,SPOP,DZIP1
    Activation of SMO IQCE,CDON,ADRBK1,GAS8,CSNK1A1,KIF3A,SETD6,EFCAB7,BOC,EVC2

    Protein Function

    EVC has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by EVC itself. We selected most functions EVC had, and list some proteins which have the same functions with EVC. You can find most of the proteins on our site.

    Function Related Protein

    Interacting Protein

    EVC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EVC here. Most of them are supplied by our site. Hope this information will be useful for your research of EVC.

    Resources

    References

    • Kusuma, S; Facklam, A; et al. Characterizing Human Pluripotent-Stem-Cell-Derived Vascular Cells for Tissue Engineering Applications. STEM CELLS AND DEVELOPMENT 24:451-458(2015).
    • Gui, DM; Li, YF; et al. HIF-1 signaling pathway involving iNOS, COX-2 and caspase-9 mediates the neuroprotection provided by erythropoietin in the retina of chronic ocular hypertension rats. MOLECULAR MEDICINE REPORTS 11:1490-1496(2015).

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