ESPN
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Official Full Name
espin -
Overview
This gene encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement. -
Synonyms
ESPN;espin;deafness, autosomal recessive 36 , DFNB36;ectoplasmic specialization protein;autosomal recessive deafness type 36 protein;DFNB36;LP2654;DKFZp434A196;DKFZp434G2126
Recombinant Proteins
- Rat
- Human
- Zebrafish
- Mouse
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- His
- GST
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ESPN-2150R | Recombinant Rat ESPN Protein | Mammalian Cell | Rat | His |
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| ESPN-3503H | Recombinant Human ESPN Protein, GST-tagged | Wheat Germ | Human | GST |
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| ESPN-6670Z | Recombinant Zebrafish ESPN | Mammalian Cell | Zebrafish | His |
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| ESPN-1807R | Recombinant Rat ESPN Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| ESPN-1807R-B | Recombinant Rat ESPN Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Espn-2871M | Recombinant Mouse Espn Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| ESPN-4412H | Recombinant Human ESPN Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| ESPN-4711HF | Recombinant Full Length Human ESPN Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 854 amino acids |
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Involved Pathway
ESPN involved in several pathways and played different roles in them. We selected most pathways ESPN participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ESPN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ESPN has several biochemical functions, for example, actin binding,actin filament binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ESPN itself. We selected most functions ESPN had, and list some proteins which have the same functions with ESPN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | MYO15,CAPZA1,ACTN4,WDR1,CNN3,MYH11A,FLII,ADD1,CXCR4,DMTN |
| actin filament binding | KLHL17,TAGLN3B,ARPC1A,MYO6,RCSD1,ADD1,PLS1,CORO1CA,EZR,ADSSL1 |
Interacting Protein
ESPN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ESPN here. Most of them are supplied by our site. Hope this information will be useful for your research of ESPN.
Resources
Related Services
Related Products
References
- Lee, JJ; Kang, CK; et al. Evaluation of shear bond strength between dual cure resin cement and zirconia ceramic after thermocycling treatment. JOURNAL OF ADVANCED PROSTHODONTICS 7:1-7(2015).
- Al-Bahrani, A; Patel, D; et al. Using ESPN 30 for 30 to Teach Economics. SOUTHERN ECONOMIC JOURNAL 81:829-842(2015).
