ESD

  • Official Full Name

    esterase D

  • Overview

    This gene encodes a serine hydrolase that belongs to the esterase D family. The encoded enzyme is active toward numerous substrates including O-acetylated sialic acids, and it may be involved in the recycling of sialic acids. This gene is used as a genetic marker for retinoblastoma and Wilsons disease.

  • Synonyms

    ESD;esterase D;esterase D/formylglutathione hydrolase;S-formylglutathione hydrolase;S formylglutathione hydrolase;EC 3.1.2.12;Es-10;Es10;ESTD_HUMAN;Esterase 10;Esterase D formylglutathione hydrolase;FGH;FGH, included;FLJ11763;MGC139609;OTTHUMP00000018374;OTTHUMP00000040929;S-formylglutathione hydrolase, included;Sid 478;sid478

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Rat
  • Zebrafish
  • Chicken
  • Mouse
  • HEK293
  • E.coli
  • Mammalian Cell
  • Human
  • Wheat Germ
  • Mammalian cells
  • HEK293T
  • In Vitro Cell Free System
  • Non
  • GST
  • His
  • His&Fc
  • Flag
  • His&Fc&Avi
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
ESD-6541HCL Recombinant Human ESD 293 Cell Lysate HEK293 Human Non
ESD-12554H Recombinant Human ESD, GST-tagged E.coli Human GST 1-282a.a.
ESD-1503R Recombinant Rhesus monkey ESD Protein, His-tagged Mammalian Cell Rhesus macaque His
ESD-1682H Recombinant Human Esterase D, His-tagged Human Human His
ESD-2147R Recombinant Rat ESD Protein Mammalian Cell Rat His
ESD-2532Z Recombinant Zebrafish ESD Mammalian Cell Zebrafish His
ESD-27973TH Recombinant Human ESD, His-tagged E.coli Human His Full L.
ESD-3498H Recombinant Human ESD Protein, GST-tagged Wheat Germ Human GST
ESD-376H Recombinant Human Esterase D/Formylglutathione Hydrolase E.coli Human Non
ESD-5150C Recombinant Chicken ESD Mammalian Cell Chicken His
ESD-5320M Recombinant Mouse ESD Protein Mammalian Cell Mouse His
ESD-566H Recombinant Human ESD, His tagged E.coli Human His&Fc 1-282 a.a.
ESD-1173HFL Recombinant Full Length Human ESD Protein, C-Flag-tagged Mammalian cells Human Flag Full L.
ESD-1328R Recombinant Rhesus Macaque ESD Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
ESD-1328R-B Recombinant Rhesus Macaque ESD Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
ESD-1443H Recombinant Human ESD Protein, His-tagged E.coli Human His Ala2-Ala282
Esd-1444M Recombinant Mouse Esd Protein, His-tagged E.coli Mouse His Ala2-Ala282
ESD-1661H Recombinant Human ESD Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
ESD-1804R Recombinant Rat ESD Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
ESD-1804R-B Recombinant Rat ESD Protein Pre-coupled Magnetic Beads HEK293 Rat
ESD-2223H Recombinant Human ESD Protein E.coli Human Non
ESD-2863M Recombinant Mouse ESD Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
ESD-2863M-B Recombinant Mouse ESD Protein Pre-coupled Magnetic Beads HEK293 Mouse
ESD-3010H Recombinant Human ESD Protein (Met1-Ala282), N-His tagged E.coli Human His Met1-Ala282
ESD-4703HF Recombinant Full Length Human ESD Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 282 amino acids
Esd-5652M Recombinant Mouse Esd Protein (Met1-Ala282), N-His tagged E.coli Mouse His Met1-Ala282
ESD-867H Recombinant Human ESD Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
ESD-867H-B Recombinant Human ESD Protein Pre-coupled Magnetic Beads HEK293 Human
Esd-975M Recombinant Mouse Esd Protein, MYC/DDK-tagged HEK293T Mouse Myc&DDK

    Involved Pathway

    ESD involved in several pathways and played different roles in them. We selected most pathways ESD participated on our site, such as Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ESD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Carbon metabolism ENO1,IDH3B,GPI,MCEE,ACO2,AGXT,PCCA,GPT2L,FBP1B,TPI1A

    Protein Function

    ESD has several biochemical functions, for example, S-formylglutathione hydrolase activity,carboxylic ester hydrolase activity,hydrolase activity, acting on ester bonds. Some of the functions are cooperated with other proteins, some of the functions could acted by ESD itself. We selected most functions ESD had, and list some proteins which have the same functions with ESD. You can find most of the proteins on our site.

    Function Related Protein
    protein binding TAX1BP1,SULT1A1,IL6R,ERGIC2,CYB561,SPTLC1,HIST1H4C,TATDN1,MPL,BMPR1B
    hydrolase activity, acting on ester bonds APMAP,RAG1,LIPK,ACY3.2,C11orf54,PTER,ENDOU2,ACY3.1,PGAP3,ACY3
    carboxylic ester hydrolase activity Ces2c,LIPCA,LYPLAL1,AADACL4,NCEH1,CES1,ACOT7,ACOT12,ACOT1,NCEH1A
    methylumbelliferyl-acetate deacetylase activity CES1,CES2

    Interacting Protein

    ESD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ESD here. Most of them are supplied by our site. Hope this information will be useful for your research of ESD.

    FSD2;MCC;HLA-B;DDA1;TRAF6;PLCG2;CRK;GRB2;VCAM1;HDAC1

    Resources

    References

    • De Vitis, V; Guidi, B; et al. Marine Microorganisms as Source of Stereoselective Esterases and Ketoreductases: Kinetic Resolution of a Prostaglandin Intermediate. MARINE BIOTECHNOLOGY 17:144-152(2015).
    • Gunter, EA; Shkryl, YN; et al. Cell-wall polysaccharide composition and glycanase activity of Silene vulgaris callus transformed with rolB and rolC genes. CARBOHYDRATE POLYMERS 118:52-59(2015).

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